Carcinogenesis is accompanied by widespread DNA methylation changes within the cell.
These changes are characterized by a globally hypomethylated genome with focal …

In the burgeoning field of epigenetics, there are several methods available to determine the
methylation status of DNA samples. However, choosing the method that is best suited to …

Epigenetic silencing is a natural phenomenon in which the expression of genes is regulated
through modifications of DNA, RNA, or histone proteins. It is a mechanism for defending host …

Patients diagnosed with epithelial ovarian cancer (OC) have a 5-year survival rate of 49%.
For early-stage disease, the 5-year survival rate is above 90%. However, advanced-stage …

Dietary interventions like gluten-free and casein-free diets have been reported to improve
intestinal, autoimmune and neurological symptoms in patients with a variety of conditions; …

Major histocompatibility complex (MHC) molecules are key players in initiating immune
responses towards invading pathogens. Both MHC class I and class II genes are present in …

Purpose: Epigenetic host cell changes involved in cervical cancer development following a
persistent high-risk human papillomavirus (hrHPV) infection, provide promising markers for …

Abstract Background Free circulating DNA (fcDNA) has many potential clinical applications,
due to the non-invasive way in which it is collected. However, because of the low …

Background Assessment of DNA promoter methylation markers in cervical scrapings for the
detection of cervical intraepithelial neoplasia (CIN) and cervical cancer is feasible, but …

Next‐generation sequencing (NGS) technologies have greatly impacted on every field of
molecular research mainly because they reduce costs and increase throughput of DNA …