Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation
X Chen, R Wu, L Li, Y Zeng, J Chen, M Wei, Y Feng… - Immunity, 2023 - cell.com
The physiological and immune changes that occur during pregnancy are associated with
worsened disease outcomes during infection and sepsis. How these perturbations …
worsened disease outcomes during infection and sepsis. How these perturbations …
Mitochondrial dysfunction as a signaling target for therapeutic intervention in major neurodegenerative disease
SV Mangrulkar, NL Wankhede, MB Kale… - Neurotoxicity …, 2023 - Springer
Neurodegenerative diseases (NDD) are incurable and the most prevalent cognitive and
motor disorders of elderly. Mitochondria are essential for a wide range of cellular processes …
motor disorders of elderly. Mitochondria are essential for a wide range of cellular processes …
Navigating the Intersection: Diabetes and Alzheimer's Intertwined Relationship
MB Kale, HM Bhondge, NL Wankhede… - Ageing Research …, 2024 - Elsevier
Alzheimer's disease (AD) and Diabetes mellitus (DM) exhibit comparable
pathophysiological pathways. Genetic abnormalities in APP, PS-1, and PS-2 are linked to …
pathophysiological pathways. Genetic abnormalities in APP, PS-1, and PS-2 are linked to …
Molecular understanding of ER-MT communication dysfunction during neurodegeneration
SS Sammeta, TA Banarase, SR Rahangdale… - Mitochondrion, 2023 - Elsevier
Biological researchers are seeing organelles in a new light. These cellular entities have
been believed to be singular and distinctive structures that performed specialized purposes …
been believed to be singular and distinctive structures that performed specialized purposes …
Mitophagy regulation in aging and neurodegenerative disease
TA Banarase, SS Sammeta, NL Wankhede… - Biophysical …, 2023 - Springer
Mitochondria are the primary cellular energy generators, supplying the majority of
adenosine triphosphate through oxidative phosphorylation, which is necessary for neuron …
adenosine triphosphate through oxidative phosphorylation, which is necessary for neuron …
Decoding mitochondrial quality control mechanisms: Identifying treatment targets for enhanced cellular health
NL Wankhede, SR Kopalli, MD Dhokne, DJ Badnag… - Mitochondrion, 2024 - Elsevier
Mitochondria are singular cell organelles essential for many cellular functions, which
includes responding to stress, regulating calcium levels, maintaining protein homeostasis …
includes responding to stress, regulating calcium levels, maintaining protein homeostasis …
Unraveling the nexus of age, epilepsy, and mitochondria: exploring the dynamics of cellular energy and excitability
Epilepsy, a complex neurological condition marked by recurring seizures, is increasingly
recognized for its intricate relationship with mitochondria, the cellular powerhouses …
recognized for its intricate relationship with mitochondria, the cellular powerhouses …
Protein research may hint at how human eggs survive for decades
C Szalinski - Proceedings of the National Academy of Sciences, 2024 - pnas.org
Human eggs, called oocytes, have a superpower: They can stay in the ovaries for decades,
from before a woman is born until she's over age 40. Most of our cells are constantly turning …
from before a woman is born until she's over age 40. Most of our cells are constantly turning …
Decoding the therapeutic potential of cannabis and cannabinoids in neurological disorders
MB Kale, MD Umare, NL Wankhede… - Current …, 2024 - benthamdirect.com
For millennia, Cannabis sativa has served diverse roles, from medicinal applications to
recreational use. Despite its extensive historical use, only a fraction of its components have …
recreational use. Despite its extensive historical use, only a fraction of its components have …
A compendium for novel marker-based breeding strategies in eggplant
The worldwide production of eggplant is estimated at about 58 Mt, with China, India and
Egypt being the major producing countries. Breeding efforts in the species have mainly …
Egypt being the major producing countries. Breeding efforts in the species have mainly …