While the application of cryogenic electron microscopy (cryo-EM) to helical polymers in
biology has a long history, due to the huge number of helical macromolecular assemblies in …

The self-assembly of molecules in two dimensions (2D) is gathering attention from all
disciplines across the chemical sciences. Attracted by the interesting properties of two …

Assembly ubiquitously occurs in nature and gives birth to numerous functional biomaterials
and sophisticated organisms. In this work, chiral hydrogen-bonded organic-inorganic …

Cell spheroids bridge the discontinuity between in vitro systems and in vivo animal models.
However, inducing cell spheroids by nanomaterials remains an inefficient and poorly …

The Golgi apparatus (GA) is the hub of intracellular trafficking, but selectively targeting GA
remains a challenge. We show an unconventional types of peptide thioesters, consisting of …

Chirality, an inherent characteristic observed throughout nature, plays a pivotal role across a
wide range of scales, from subatomic to galactic, and holds significance in myriad scientific …

The understanding of how short peptide assemblies transit from disorder to order remains
limited due to the lack of atomistic structures. Here, we report the cryo-EM structure of the …

Functional and versatile nano-and microassemblies formed by biological molecules are
found at all levels of life, from cell organelles to full organisms. Understanding the chemical …

Self-assembly is the most suitable approach to obtaining peptide-based materials on the
nano-and mesoscopic scales. Applications span from peptide drugs for personalized …

The ability to engineer synthetic polymers with the same structural precision as
biomacromolecules is crucial to enable the de novo design of robust nanomaterials with …