Non-lethal sampling for assessment of mitochondrial function does not affect metabolic rate and swimming performance

E Thoral, L Dargère… - … of the Royal …, 2024 - royalsocietypublishing.org
A fundamental issue in the metabolic field is whether it is possible to understand underlying
mechanisms that characterize individual variation. Whole-animal performance relies on …

Exhaustive exercise alters native and site-specific H2O2 emission in red and white skeletal muscle mitochondria

C Kamunde, Y Wijayakulathilake, C Okoye… - Free Radical Biology …, 2023 - Elsevier
Mitochondrial reactive oxygen species (ROS) homeostasis is intricately linked to energy
conversion reactions and entails regulation of the mechanisms of ROS production and …

Oral pyruvate prevents high-intensity interval exercise-induced metabolic acidosis in rats by promoting lactate dehydrogenase reaction

K Che, Y Yang, J Zhang, L Feng, Y Xie, Q Li… - Frontiers in Nutrition, 2023 - frontiersin.org
Introduction There is no denying the clinical benefits of exogenous pyruvate in the treatment
of pathological metabolic acidosis. However, whether it can prevent exercise physiological …

Prolonged treatment with a PI3K p110α inhibitor causes sex-and tissue-dependent changes in antioxidant content, but does not affect mitochondrial function

CP Hedges, T Pham, B Shetty, SWC Masson… - Bioscience …, 2020 - portlandpress.com
Genetic inhibition of the p110α isoform of phosphatidylinositol-3-kinase (PI3K) can increase
murine lifespan, enhance mitochondrial function and alter tissue-specific oxidative balance …

[HTML][HTML] The effect of voluntary wheel running on the antioxidant status is dependent on sociability conditions

MP Cunha, DG Machado, G Mancini, V Glaser… - Pharmacology …, 2020 - Elsevier
Voluntary wheel running is widely used as a physical activity (PA) model in rodents, but most
studies investigate the beneficial effects of this intervention in socially isolated mice. Social …