Chemically modified biomacromolecules─ ie, proteins, nucleic acids, glycans, and lipids─
have become crucial tools in chemical biology. They are extensively used not only to …

Photoremovable Protecting Groups in Chemistry and Biology: Reaction Mechanisms and
Efficacy | Chemical Reviews ACS ACS Publications C&EN CAS Find my institution Log In …

Controlling the conformation and activity of biomolecules in a reversible manner is a
fascinating challenge (1-3) that has an outstanding potential for the study of and interference …

The photoisomerization of azobenzene has been known for almost 75 years but only
recently has this process been widely applied to biological systems. The central challenge of …

Spatial and temporal control over chemical and biological processes plays a key role in life,
where the whole is often much more than the sum of its parts. Quite trivially, the molecules of …

Photoresponsive nucleic acids attract growing interest as functional constituents in materials
science. Integration of photoisomerizable units into DNA strands provides an ideal handle …

High temporal and spatial regulation of cellular activities, biological pathways, and gene
expression is critical in complex biological processes.[1] One remarkable technique that …

Controlled activation or release of biomolecules is very crucial in various biological
applications. Controlling the activity of biomolecules have been attempted by various means …

The ability to remotely trigger CRISPR/Cas9 activity would enable new strategies to study
cellular events with greater precision and complexity. In this work, we have developed a …

The current available therapeutics face several challenges such as the development of ideal
drug delivery systems towards the goal of personalized treatments for patients benefit. The …