Polyethylene glycol or PEG has a long history of use in medicine. Many conventional
formulations utilize PEG as either an active ingredient or an excipient. PEG found its use in …

Polyethylene glycol (PEG) is a versatile polymer that is widely used as an additive in foods
and cosmetics, and as a carrier in PEGylated therapeutics. Even though PEG is thought to …

Conjugation of polyethylene glycols (PEGs) to proteins or drug delivery nanosystems is a
widely accepted method to increase the therapeutic index of complex nano …

Polyethylene glycol (PEG)-coated nanopharmaceuticals can cause mild to severe
hypersensitivity reactions (HSRs), which can occasionally be life threatening or even lethal …

The interactions between polymers and the immune system remains poorly controlled. In
some instances, the immune system can produce antibodies specific to polymer …

This study addresses well-known shortcomings of poly (ethylene glycol)(PEG)-based
conjugates. PEGylation is by far the most common method employed to overcome …

Breast cancer is the most frequent female malignancy worldwide. Current strategies in
breast cancer therapy, including classical chemotherapy, hormone therapy, and targeted …

The radioprotective capacity of a rationally-designed Mn2+-decapeptide complex (MDP),
based on Mn antioxidants in the bacterium Deinococcus radiodurans, was investigated in a …

Human granulocyte colony-stimulating factor (G-CSF) is a granulopoietic growth factor used
in the treatment of neutropenia following chemotherapy, myeloablative treatment, or healthy …

Objectives: Identify the mechanism of pegfilgrastim. Summarize the indications for using
pegfilgrastim. Review the adverse event profile of pegfilgrastim. Outline the importance of …