Chloroplast genomes: diversity, evolution, and applications in genetic engineering

H Daniell, CS Lin, M Yu, WJ Chang - Genome biology, 2016 - Springer
Chloroplasts play a crucial role in sustaining life on earth. The availability of over 800
sequenced chloroplast genomes from a variety of land plants has enhanced our …

Green giant—a tiny chloroplast genome with mighty power to produce high‐value proteins: history and phylogeny

H Daniell, S Jin, XG Zhu… - Plant biotechnology …, 2021 - Wiley Online Library
Free‐living cyanobacteria were entrapped by eukaryotic cells~ 2 billion years ago, ultimately
giving rise to chloroplasts. After a century of debate, the presence of chloroplast DNA was …

Engineering plastid genomes: methods, tools, and applications in basic research and biotechnology

R Bock - Annual Review of Plant Biology, 2015 - annualreviews.org
The small bacterial-type genome of the plastid (chloroplast) can be engineered by genetic
transformation, generating cells and plants with transgenic plastid genomes, also referred to …

Bioinspired oral delivery devices

X Zhang, G Chen, H Zhang, L Shang… - Nature Reviews …, 2023 - nature.com
Oral administration is a widespread and convenient drug delivery approach. However, oral
delivery can be affected by the complex digestive tract environment, including irregular …

Nutritionally enhanced food crops; progress and perspectives

KL Hefferon - International journal of molecular sciences, 2015 - mdpi.com
Great progress has been made over the past decade with respect to the application of
biotechnology to generate nutritionally improved food crops. Biofortified staple crops such as …

The engineered chloroplast genome just got smarter

S Jin, H Daniell - Trends in plant science, 2015 - cell.com
Chloroplasts are known to sustain life on earth by providing food, fuel, and oxygen through
the process of photosynthesis. However, the chloroplast genome has also been smartly …

Expression systems for heterologous production of antimicrobial peptides

NS Parachin, KC Mulder, AAB Viana, SC Dias… - Peptides, 2012 - Elsevier
Antimicrobial peptides (AMPs) consist of molecules that act on the defense systems of
numerous organisms toward multiple pathogens such as bacteria, fungi, parasites and …

Plant‐made oral vaccines against human infectious diseases—are we there yet?

HT Chan, H Daniell - Plant biotechnology journal, 2015 - Wiley Online Library
Although the plant‐made vaccine field started three decades ago with the promise of
developing low‐cost vaccines to prevent infectious disease outbreaks and epidemics …

Engineered chloroplast dsRNA silences cytochrome p450 monooxygenase, V‐ATPase and chitin synthase genes in the insect gut and disrupts Helicoverpa armigera …

S Jin, ND Singh, L Li, X Zhang… - Plant biotechnology …, 2015 - Wiley Online Library
In the past two decades, chloroplast genetic engineering has been advanced to achieve
high‐level protein accumulation but not for down‐regulation of targeted genes. Therefore, in …

MoChlo: a versatile, modular cloning toolbox for chloroplast biotechnology

A Occhialini, AA Piatek, AC Pfotenhauer… - Plant …, 2019 - academic.oup.com
Plant synthetic biology is a rapidly evolving field with new tools constantly emerging to drive
innovation. Of particular interest is the application of synthetic biology to chloroplast …