Persistent human papillomavirus infection

AN Della Fera, A Warburton, TL Coursey, S Khurana… - Viruses, 2021 - mdpi.com
Simple Summary The success of HPV as an infectious agent lies not within its ability to
cause disease, but rather in the adeptness of the virus to establish long-term persistent …

APOBEC: A molecular driver in cervical cancer pathogenesis

S Revathidevi, AK Murugan, H Nakaoka, I Inoue… - Cancer letters, 2021 - Elsevier
Cervical cancer is one of the foremost common cancers in women. Human papillomavirus
(HPV) infection remains a major risk factor of cervical cancer. In addition, numerous other …

Multiple lineages of monkeypox virus detected in the United States, 2021–2022

CM Gigante, B Korber, MH Seabolt, K Wilkins… - Science, 2022 - science.org
Monkeypox is a viral zoonotic disease endemic in Central and West Africa. In May 2022,
dozens of non-endemic countries reported hundreds of monkeypox cases, most with no …

No evidence for increased transmissibility from recurrent mutations in SARS-CoV-2

L van Dorp, D Richard, CCS Tan, LP Shaw… - Nature …, 2020 - nature.com
COVID-19 is caused by the coronavirus SARS-CoV-2, which jumped into the human
population in late 2019 from a currently uncharacterised animal reservoir. Due to this recent …

High-risk human papillomaviral oncogenes E6 and E7 target key cellular pathways to achieve oncogenesis

NSL Yeo-Teh, Y Ito, S Jha - International journal of molecular sciences, 2018 - mdpi.com
Infection with high-risk human papillomavirus (HPV) has been linked to several human
cancers, the most prominent of which is cervical cancer. The integration of the viral genome …

Human papillomavirus genomics: Understanding carcinogenicity

CW Nelson, L Mirabello - Tumour Virus Research, 2023 - Elsevier
Human papillomavirus (HPV) causes virtually all cervical cancers and many cancers at other
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …

[HTML][HTML] Potential APOBEC-mediated RNA editing of the genomes of SARS-CoV-2 and other coronaviruses and its impact on their longer term evolution

J Ratcliff, P Simmonds - Virology, 2021 - Elsevier
Members of the APOBEC family of cytidine deaminases show antiviral activities in
mammalian cells through lethal editing in the genomes of small DNA viruses, herpesviruses …

[HTML][HTML] Evasion of host immune defenses by human papillomavirus

JA Westrich, CJ Warren, D Pyeon - Virus research, 2017 - Elsevier
A majority of human papillomavirus (HPV) infections are asymptomatic and self-resolving in
the absence of medical interventions. Various innate and adaptive immune responses, as …

Footprint of the host restriction factors APOBEC3 on the genome of human viruses

F Poulain, N Lejeune, K Willemart, NA Gillet - PloS pathogens, 2020 - journals.plos.org
APOBEC3 enzymes are innate immune effectors that introduce mutations into viral
genomes. These enzymes are cytidine deaminases which transform cytosine into uracil …

[HTML][HTML] Roles of APOBEC3A and APOBEC3B in human papillomavirus infection and disease progression

CJ Warren, JA Westrich, KV Doorslaer, D Pyeon - Viruses, 2017 - mdpi.com
The apolipoprotein B messenger RNA-editing, enzyme-catalytic, polypeptide-like 3
(APOBEC3) family of cytidine deaminases plays an important role in the innate immune …