Medicinal plants utilized in Thai Traditional Medicine for diabetes treatment: Ethnobotanical surveys, scientific evidence and phytochemicals

C Andrade, NGM Gomes, S Duangsrisai… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Diabetes mellitus remains the most lethal metabolic
disease of contemporaneous times and despite the therapeutic arsenal currently available …

A comprehensive review on synthesis, biological profile and photophysical studies of heterocyclic compounds derived from 2, 3-diamino-1, 4-naphthoquinone

M Devi, P Kumar, R Singh, L Narayan, A Kumar… - Journal of Molecular …, 2022 - Elsevier
Abstract The 1, 4-naphthoquinone skeleton is an important pharmacophoric unit found in
many biologically active natural products and many well-known chemotherapy agents, such …

Quercetin ameliorates oxidative stress, inflammation and apoptosis in the heart of streptozotocin-nicotinamide-induced adult male diabetic rats

J Roslan, N Giribabu, K Karim, N Salleh - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Introduction Quercetin is known to possess beneficial effects in ameliorating diabetic
complications, however the mechanisms underlying cardioprotective effect of this compound …

Solid lipid nanoparticles of myricitrin have antioxidant and antidiabetic effects on streptozotocin‐nicotinamide‐induced diabetic model and myotube cell of male …

A Ahangarpour, AA Oroojan… - Oxidative medicine …, 2018 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) may occur via oxidative stress. Myricitrin is a plant‐derived
antioxidant, and its solid lipid nanoparticle (SLN) may be more potent. Hence, the present …

Design, synthesis, spectroscopic characterization, single crystal X-ray analysis, in vitro α-amylase inhibition assay, DPPH free radical evaluation and computational …

M Devi, P Kumar, R Singh, J Sindhu… - European Journal of …, 2023 - Elsevier
In our quest to design and develop N/O-containing inhibitors of α-amylase, we have tried to
synergize the inhibitory action of 1, 4-naphthoquinone, imidazole and 1, 2, 3-triazole motifs …

Phyllanthus niruri leaves aqueous extract improves kidney functions, ameliorates kidney oxidative stress, inflammation, fibrosis and apoptosis and enhances kidney …

N Giribabu, K Karim, EK Kilari, N Salleh - Journal of ethnopharmacology, 2017 - Elsevier
Ethnopharmacological relevance Phylanthus niruri has been used to treat ailments related
to the urogenital organs. In this study, this herb was hypothesized to help to ameliorate …

Discovery potent of thiazolidinedione derivatives as antioxidant, α-amylase inhibitor, and antidiabetic agent

MY Sameeh, MM Khowdiary, HS Nassar, MM Abdelall… - Biomedicines, 2021 - mdpi.com
This work aimed to synthesize safe antihyperglycemic derivatives bearing thiazolidinedione
fragment based on spectral data. The DFT theory discussed the frontier molecular orbitals …

[PDF][PDF] In vivo administration of quercetin ameliorates sperm oxidative stress, inflammation, preserves sperm morphology and functions in streptozotocin-nicotinamide …

S Yelumalai, N Giribabu, K Karim, SZ Omar… - Archives of Medical …, 2019 - termedia.pl
Results In diabetic rats receiving quercetin, sperm count and motility, viability and HOS tail-
coiled sperm increased (p< 0.05) while sperm with abnormal morphology decreased …

[HTML][HTML] Anti-hyperglycemic and anti-hyperlipidemic effects of rhinacanthins-rich extract from Rhinacanthus nasutus leaves in nicotinamide-streptozotocin induced …

MA Shah, W Reanmongkol, N Radenahmad… - Biomedicine & …, 2019 - Elsevier
Rhinacanthus nasutus has traditionally been used in the treatment of various disorders
including diabetes mellitus. Rhinacanthins-rich extract (RRE) is a semipurified R. nasutus …

α-Glucosidase inhibitory effect of rhinacanthins-rich extract from Rhinacanthus nasutus leaf and synergistic effect in combination with acarbose

MA Shah, R Khalil, Z Ul-Haq… - Journal of Functional …, 2017 - Elsevier
Rhinacanthins-rich extract (RRE) from Rhinacanthus nasutus leaf and its marker
compounds namely rhinacanthin-C, rhinacanthin-D and rhinacanthin-N were evaluated for α …