Isothermal amplification of nucleic acids
Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …
Advancement of the emerging field of RNA nanotechnology
The field of RNA nanotechnology has advanced rapidly during the past decade. A variety of
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …
programmable RNA nanoparticles with defined shape, size, and stoichiometry have been …
RNA-polymer hybrids via direct and site-selective acylation with the ATRP initiator and photoinduced polymerization
Combining synthetic polymers with RNA paves the way for creating RNA-based materials
with non-canonical functions. We have developed an acylation reagent that allows for direct …
with non-canonical functions. We have developed an acylation reagent that allows for direct …
Systemic delivery of anti-miRNA for suppression of triple negative breast cancer utilizing RNA nanotechnology
MicroRNAs play important roles in regulating the gene expression and life cycle of cancer
cells. In particular, miR-21, an oncogenic miRNA is a major player involved in tumor …
cells. In particular, miR-21, an oncogenic miRNA is a major player involved in tumor …
Multifunctional rolling circle transcription-based nanomaterials for advanced drug delivery
X Ma, Y Zhang, K Huang, L Zhu, W Xu - Biomaterials, 2023 - Elsevier
As the up-and-comer in the development of RNA nanotechnology, RNA nanomaterials
based on functionalized rolling circle transcription (RCT) have become promising carriers for …
based on functionalized rolling circle transcription (RCT) have become promising carriers for …
Biomass RNA for the Controlled Synthesis of Degradable Networks by Radical Polymerization
Nucleic acids extracted from biomass have emerged as sustainable and environmentally
friendly building blocks for the fabrication of multifunctional materials. Until recently, the …
friendly building blocks for the fabrication of multifunctional materials. Until recently, the …
RNA nanoparticles as rubber for compelling vessel extravasation to enhance tumor targeting and for fast renal excretion to reduce toxicity
Rubber is a fascinating material in both industry and daily life. The development of
elastomeric material in nanotechnology is imperative due to its economic and technological …
elastomeric material in nanotechnology is imperative due to its economic and technological …
DNA droplets: intelligent, dynamic fluid
Breathtaking advances in DNA nanotechnology have established DNA as a promising
biomaterial for the fabrication of programmable higher‐order nano/microstructures. In the …
biomaterial for the fabrication of programmable higher‐order nano/microstructures. In the …
[HTML][HTML] RNA as a stable polymer to build controllable and defined nanostructures for material and biomedical applications
The value of polymers is manifested in their vital use as building blocks in material and life
sciences. Ribonucleic acid (RNA) is a polynucleic acid, but its polymeric nature in materials …
sciences. Ribonucleic acid (RNA) is a polynucleic acid, but its polymeric nature in materials …
Comb-structured mRNA vaccine tethered with short double-stranded RNA adjuvants maximizes cellular immunity for cancer treatment
TA Tockary, S Abbasi, M Matsui-Masai… - Proceedings of the …, 2023 - National Acad Sciences
Integrating antigen-encoding mRNA (Messenger RNA) and immunostimulatory adjuvant into
a single formulation is a promising approach to potentiating the efficacy of mRNA vaccines …
a single formulation is a promising approach to potentiating the efficacy of mRNA vaccines …