Many medical devices such as cardiopulmonary bypass systems, mechanical heart valves,
or ventricular assist devices are intended to come into contact with blood flow during use. In …

Background Left ventricular assist devices (LVADs) have been used as a standard treatment
option for patients with advanced heart failure. However, these devices are prone to adverse …

In vitro hemolysis testing is commonly used to determine hemocompatibility of
ExtraCorporeal Membrane Oxygenation (ECMO). However, poor reproducibility remains a …

The development of adult use right ventricular assist devices (RVADs) and pediatric left
ventricular assist devices (pediatric LVADs) have significantly lagged behind compared to …

Background The major obstacle of blood‐contacting medical devices is insufficient
hemocompatibility, particularly thrombogenicity and platelet activation. Pre‐clinical in‐vitro …

Graphical abstract: Rheological understanding of blood is relevant for the design of
cardiovascular medical devices and implants. Erythrocytes are represented by hydrogel …

Heart failure (HF) is a public health burden. In the next ten years, 8 million Americans are
expected to have HF. A subset of these patients will develop advanced HF. They are …

The development of adult use right ventricular assist devices (RVADs) and pediatric left
ventricular assist devices (pediatric LVADs) have significantly lagged behind compared to …

Abstract Left Ventricular Assist Devices (LVADs) are mechanical pumps used to treat heart
failure, which is the cause of 6.2 million deaths in the United States every year. Despite …