The impact of ageing on monocytes and macrophages

RPH De Maeyer, ES Chambers - Immunology letters, 2021 - Elsevier
Ageing is a global burden. Increasing age is associated with increased incidence of
infections and cancer and decreased vaccine efficacy. This increased morbidity observed …

Inflammatory mechanisms in patients with chronic obstructive pulmonary disease

PJ Barnes - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Chronic obstructive pulmonary disease (COPD) is associated with chronic inflammation
affecting predominantly the lung parenchyma and peripheral airways that results in largely …

Overview of the mechanisms of oxidative stress: impact in inflammation of the airway diseases

GD Albano, RP Gagliardo, AM Montalbano, M Profita - Antioxidants, 2022 - mdpi.com
Inflammation of the human lung is mediated in response to different stimuli (eg, physical,
radioactive, infective, pro-allergenic or toxic) such as cigarette smoke and environmental …

Cellular and molecular mechanisms of asthma and COPD

PJ Barnes - Clinical science, 2017 - portlandpress.com
Asthma and chronic obstructive pulmonary disease (COPD) both cause airway obstruction
and are associated with chronic inflammation of the airways. However, the nature and sites …

Epithelial barrier dysfunction in chronic respiratory diseases

FM Carlier, C de Fays, C Pilette - Frontiers in physiology, 2021 - frontiersin.org
Mucosal surfaces are lined by epithelial cells, which provide a complex and adaptive
module that ensures first-line defense against external toxics, irritants, antigens, and …

Cellular and molecular mechanisms of chronic obstructive pulmonary disease

PJ Barnes - Clinics in chest medicine, 2014 - chestmed.theclinics.com
Chronic obstructive pulmonary disease (COPD) involves chronic inflammation of the lung,
particularly in peripheral airways and parenchyma, which increases during acute …

Understanding acquired brain injury: a review

L Goldman, EM Siddiqui, A Khan, S Jahan… - Biomedicines, 2022 - mdpi.com
Any type of brain injury that transpires post-birth is referred to as Acquired Brain Injury (ABI).
In general, ABI does not result from congenital disorders, degenerative diseases, or by brain …

Curcumin use in pulmonary diseases: State of the art and future perspectives

D Lelli, A Sahebkar, TP Johnston, C Pedone - Pharmacological research, 2017 - Elsevier
Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma
longa). It has been used for centuries in Ayurveda (Indian traditional medicine) for the …

Oxidative stress in COPD: sources, markers, and potential mechanisms

AJA McGuinness, E Sapey - Journal of clinical medicine, 2017 - mdpi.com
Markers of oxidative stress are increased in chronic obstructive pulmonary disease (COPD)
and reactive oxygen species (ROS) are able to alter biological molecules, signaling …

Chronic obstructive pulmonary disease: molecular and cellularmechanisms

PJ Barnes, SD Shapiro… - European Respiratory …, 2003 - Eur Respiratory Soc
Chronic obstructive pulmonary disease is a leading cause of death and disability, but has
only recently been extensively explored from a cellular and molecular perspective. There is …