Ca2+-release channels are giant membrane proteins that control the release of Ca2+ from
the endoplasmic and sarcoplasmic reticulum. The two members, ryanodine receptors …

The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

Ryanodine receptors (RyRs) are located in the sarcoplasmic/endoplasmic reticulum
membrane and are responsible for the release of Ca2+ from intracellular stores during …

Large-conductance Ca2+ release channels known as ryanodine receptors (RyRs) mediate
the release of Ca2+ from an intracellular membrane compartment, the endo/sarcoplasmic …

Ryanodine receptors (RyRs) are huge ion channels that are responsible for the release of
Ca 2+ from the sarco/endoplasmic reticulum. RyRs form homotetramers with a mushroom …

Chronic low-level polychlorinated biphenyl (PCB) exposures remain a significant public
health concern since results from epidemiological studies indicate that PCB burden is …

The endoplasmic reticulum (ER) and sarcoplasmic reticulum (SR) form major intracellular
Ca 2+ stores. Ryanodine receptors (RyRs) are large tetrameric ion channels in the SR and …

Calmodulin (CaM) is the principal Ca2+ sensor protein in all eukaryotic cells, that upon
binding to target proteins transduces signals encoded by global or subcellular-specific …

S100A1, a small homodimeric EF-hand Ca2+-binding protein (~ 21 kDa), plays an important
regulatory role in Ca2+ signaling pathways involved in various biological functions including …

The exceptional versatility of calmodulin (CaM) three-dimensional arrangement is reflected
in the growing number of structural models of CaM/protein complexes currently available in …