Humans require a plethora of higher cognitive skills to perform executive functions, such as
reasoning, planning, language and social interactions, which are regulated predominantly …

The discovery of neuronal systems dedicated to computing spatial information, composed of
functionally distinct cell types such as place and grid cells, combined with an extensive body …

Exercise is a non-pharmacological strategy to mitigate the deleterious effects of aging on
brain health. However, a large amount of variation exists in its efficacy. Sex of participants …

It is well established that estrogens affect neuroplasticity in a number of brain regions. In
particular, estrogens modulate and mediate spine and synapse formation as well as …

Sex differences in neurological disease extend from incidence, severity, progression and
symptoms and may ultimately influence treatment. Cognitive disturbances are frequent in …

Alterations in inhibitory interneurons contribute to cognitive deficits associated with several
psychiatric and neurological diseases. Phasic and tonic inhibition imparted by γ …

Brain networks that engage the hippocampus and prefrontal cortex are central for enabling
effective interactions with our environment. Some of the cognitive processes that these …

Cognitive functions that require the prefrontal cortex are highly sensitive to aging in humans,
nonhuman primates, and rodents, although the neurobiological correlates of this …

Executive functions supported by prefrontal cortical (PFC) systems provide essential control
and planning mechanisms to guide goal-directed behavior. As such, age-related alterations …

Background: In recent decades, the interest in behavioral interventions has been growing
due to the higher prevalence of age-related cognitive impairments. Hence, behavioral …