The structural biochemistry of the superoxide dismutases
The discovery of superoxide dismutases (SODs), which convert superoxide radicals to
molecular oxygen and hydrogen peroxide, has been termed the most important discovery of …
molecular oxygen and hydrogen peroxide, has been termed the most important discovery of …
The redox biology of schistosome parasites and applications for drug development
HH Huang, C Rigouin… - Current pharmaceutical …, 2012 - ingentaconnect.com
Schistosomiasis caused by Schistosoma spp. is a serious public health concern, especially
in sub-Saharan Africa. Praziquantel is the only drug currently administrated to treat this …
in sub-Saharan Africa. Praziquantel is the only drug currently administrated to treat this …
Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS
BR Roberts, JA Tainer, ED Getzoff, DA Malencik… - Journal of molecular …, 2007 - Elsevier
Over 130 mutations to copper, zinc superoxide dismutase (SOD) are implicated in the
selective death of motor neurons found in 25% of patients with familial amyotrophic lateral …
selective death of motor neurons found in 25% of patients with familial amyotrophic lateral …
Excretory–secretory proteome of larval Schistosoma mansoni and Echinostoma caproni, two parasites of Biomphalaria glabrata
F Guillou, E Roger, Y Moné, A Rognon… - Molecular and …, 2007 - Elsevier
Schistosoma mansoni and Echinostoma caproni are two trematode species that use
different strategies (mimicry and immunosuppression, respectively) to interfere with the snail …
different strategies (mimicry and immunosuppression, respectively) to interfere with the snail …
Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis
DS Shin, M DiDonato, DP Barondeau, GL Hura… - Journal of molecular …, 2009 - Elsevier
Prokaryotic thermophiles supply stable human protein homologs for structural biology; yet,
eukaryotic thermophiles would provide more similar macromolecules plus those missing in …
eukaryotic thermophiles would provide more similar macromolecules plus those missing in …
Superoxide Dismutases (SODs) and their role in regulating abiotic stress induced oxidative stress in plants
In plants, several metabolic pathways and premature electron leakage from the electron
transport chain of chloroplasts, mitochondria, and plasma membranes to O2 inevitably …
transport chain of chloroplasts, mitochondria, and plasma membranes to O2 inevitably …
Multiscale conformational heterogeneity in staphylococcal protein a: possible determinant of functional plasticity
LN Deis, CW Pemble, Y Qi, A Hagarman… - Structure, 2014 - cell.com
The Staphylococcus aureus virulence factor staphylococcal protein A (SpA) is a major
contributor to bacterial evasion of the host immune system, through high-affinity binding to …
contributor to bacterial evasion of the host immune system, through high-affinity binding to …
[HTML][HTML] The somatic proteins of Toxocara canis larvae and excretory-secretory products revealed by proteomics
MB da Silva, Y Oviedo, PJ Cooper, LGC Pacheco… - Veterinary …, 2018 - Elsevier
Toxocariasis is a widespread helminth infection of dogs and cats, caused by Toxocara canis
and Toxocara cati larvae, respectively. Toxocara spp. can cause zoonotic infections in …
and Toxocara cati larvae, respectively. Toxocara spp. can cause zoonotic infections in …
Molecular determinants of compatibility polymorphism in the Biomphalaria glabrata/Schistosoma mansoni model: new candidates identified by a global comparative …
The co-evolutionary dynamics that exist in host–parasite interactions sometimes lead to
compatibility polymorphisms, the molecular bases of which are rarely investigated. To …
compatibility polymorphisms, the molecular bases of which are rarely investigated. To …
Trichuris trichiura egg extract proteome reveals potential diagnostic targets and immunomodulators
K Cruz, A Marcilla, P Kelly, M Vandenplas… - PLoS neglected …, 2021 - journals.plos.org
Embryonated eggs are the infectious developmental stage of Trichuris trichiura and are the
primary stimulus for the immune system of the definitive host. The intestinal-dwelling T …
primary stimulus for the immune system of the definitive host. The intestinal-dwelling T …