The structural biochemistry of the superoxide dismutases

JJP Perry, DS Shin, ED Getzoff, JA Tainer - Biochimica et Biophysica Acta …, 2010 - Elsevier
The discovery of superoxide dismutases (SODs), which convert superoxide radicals to
molecular oxygen and hydrogen peroxide, has been termed the most important discovery of …

The redox biology of schistosome parasites and applications for drug development

HH Huang, C Rigouin… - Current pharmaceutical …, 2012 - ingentaconnect.com
Schistosomiasis caused by Schistosoma spp. is a serious public health concern, especially
in sub-Saharan Africa. Praziquantel is the only drug currently administrated to treat this …

Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS

BR Roberts, JA Tainer, ED Getzoff, DA Malencik… - Journal of molecular …, 2007 - Elsevier
Over 130 mutations to copper, zinc superoxide dismutase (SOD) are implicated in the
selective death of motor neurons found in 25% of patients with familial amyotrophic lateral …

Excretory–secretory proteome of larval Schistosoma mansoni and Echinostoma caproni, two parasites of Biomphalaria glabrata

F Guillou, E Roger, Y Moné, A Rognon… - Molecular and …, 2007 - Elsevier
Schistosoma mansoni and Echinostoma caproni are two trematode species that use
different strategies (mimicry and immunosuppression, respectively) to interfere with the snail …

Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis

DS Shin, M DiDonato, DP Barondeau, GL Hura… - Journal of molecular …, 2009 - Elsevier
Prokaryotic thermophiles supply stable human protein homologs for structural biology; yet,
eukaryotic thermophiles would provide more similar macromolecules plus those missing in …

Superoxide Dismutases (SODs) and their role in regulating abiotic stress induced oxidative stress in plants

P Mishra, P Sharma - … oxygen, nitrogen and sulfur species in …, 2019 - Wiley Online Library
In plants, several metabolic pathways and premature electron leakage from the electron
transport chain of chloroplasts, mitochondria, and plasma membranes to O2 inevitably …

Multiscale conformational heterogeneity in staphylococcal protein a: possible determinant of functional plasticity

LN Deis, CW Pemble, Y Qi, A Hagarman… - Structure, 2014 - cell.com
The Staphylococcus aureus virulence factor staphylococcal protein A (SpA) is a major
contributor to bacterial evasion of the host immune system, through high-affinity binding to …

[HTML][HTML] The somatic proteins of Toxocara canis larvae and excretory-secretory products revealed by proteomics

MB da Silva, Y Oviedo, PJ Cooper, LGC Pacheco… - Veterinary …, 2018 - Elsevier
Toxocariasis is a widespread helminth infection of dogs and cats, caused by Toxocara canis
and Toxocara cati larvae, respectively. Toxocara spp. can cause zoonotic infections in …

Molecular determinants of compatibility polymorphism in the Biomphalaria glabrata/Schistosoma mansoni model: new candidates identified by a global comparative …

E Roger, G Mitta, Y Moné, A Bouchut, A Rognon… - Molecular and …, 2008 - Elsevier
The co-evolutionary dynamics that exist in host–parasite interactions sometimes lead to
compatibility polymorphisms, the molecular bases of which are rarely investigated. To …

Trichuris trichiura egg extract proteome reveals potential diagnostic targets and immunomodulators

K Cruz, A Marcilla, P Kelly, M Vandenplas… - PLoS neglected …, 2021 - journals.plos.org
Embryonated eggs are the infectious developmental stage of Trichuris trichiura and are the
primary stimulus for the immune system of the definitive host. The intestinal-dwelling T …