[HTML][HTML] Protein dynamics underlying allosteric regulation

MA Astore, AS Pradhan, EH Thiede… - Current Opinion in …, 2024 - Elsevier
Allostery is the mechanism by which information and control are propagated in
biomolecules. It regulates ligand binding, chemical reactions, and conformational changes …

AlphaFold and Protein Folding: Not Dead Yet! The Frontier Is Conformational Ensembles

GR Bowman - Annual Review of Biomedical Data Science, 2024 - annualreviews.org
Like the black knight in the classic Monty Python movie, grand scientific challenges such as
protein folding are hard to finish off. Notably, AlphaFold is revolutionizing structural biology …

Conditioned protein structure prediction

T Xie, Z Song, J Huang - PRX Life, 2024 - APS
Deep-learning-based protein structure prediction has facilitated major breakthroughs in
biological sciences. However, current methods struggle with alternative conformation …