Molecular imaging has emerged at the end of the last century as an interdisciplinary method
involving in vivo imaging and molecular biology aiming at identifying living biological …

Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which
leads to elevated levels of phosphocholine and glycerophosphocholine in all types of …

After several decades of debate, it is now widely acknowledged that apoptosis, also known
as programmed cell death, is central to homoeostasis and normal development and …

MR‐visible lipids or mobile lipids are defined as lipids that are observable using proton MRS
in cells and tissues. These MR‐visible lipids are composed of triglycerides and cholesterol …

Clinical trials of new cancer drugs should ideally include measurements of parameters such
as molecular target expression, pharmacokinetic (PK) behavior, and pharmacodynamic (PD) …

The ability to identify key biomolecules and molecular changes associated with cancer
malignancy and the capacity to monitor the therapeutic outcome against these targets is …

High-resolution magic angle spinning NMR spectroscopy: Application to biomedical studies -
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One of the central hallmarks of cancer is the rapid and infinite cellular proliferation. In order
to cope with increased requirement for building blocks and energy, cancer cells develop …

Standardised proton magnetic resonance spectroscopic imaging (MRSI) was initially
developed for routine in-situ clinical assessment of human brain tumours, and its use was …

Objectives: To review the use of magnetic resonance spectroscopy (MRS) as a clinical tool
in the identification of cerebral neoplasia type and grade, as well as neoplasia in the …