l-Ascorbic acid (ASA), vitamin C, is a ubiquitous carbohydrate-like compound that has an
essential role in a number of cellular processes, such as collagen synthesis, cellular …

Cancer, a fatal disease, is also one of the main causes of death worldwide. Despite various
developments to prevent and treat cancer, the side effects of anticancer drugs remain a …

Abstract Two series of 6-(1, 2, 3-triazolyl)-2, 3-dibenzyl-l-ascorbic acid derivatives with the
hydroxyethylene (8a− 8u) and ethylidene linkers (10c− 10p) were synthesized and …

The novel C-5 substituted uracil derivatives of l-ascorbic acid were synthesized by coupling
of 5-iodouracil-4, 5-didehydro-5, 6-dideoxy-l-ascorbic acid with unsaturated stannanes …

Over production of reactive oxygen species (ROS) caused by altered redox regulation of
signaling pathways is common in many types of cancers. While PET imaging is recognized …

The novel C-5 alkynyl substituted pyrimidine (1− 11) and furo [2, 3-d] pyrimidine derivatives
(12− 22) of l-ascorbic acid were synthesized by coupling of 5-iodouracil-4 ', 5 '-didehydro-5 ' …

A combination of flow chemistry and batch-based synthetic procedures has been
successfully applied to the assembly of novel 4, 5-unsaturated L-ascorbic acid series 6a–6n …

L-Ascorbic acid, also known as vitamin C, is one of the potent naturally-occurring
antioxidants in a biological system. 1 Although ascorbic acid has a range of physiological …

Background Reactive oxygen species (ROS)-induced oxidative stress damages many
cellular components such as fatty acids, DNA, and proteins. This damage is implicated in …

Aim: The authors' aim was to improve the application of copper-catalyzed azide-alkyne
cycloaddition in the synthesis of hybrids containing biologically significant nucleobases and …