Management of breast cancer in elderly individuals: recommendations of the International Society of Geriatric Oncology

H Wildiers, I Kunkler, L Biganzoli, J Fracheboud… - The lancet …, 2007 - thelancet.com
Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer
mortality in women worldwide. Elderly individuals make up a large part of the breast cancer …

[HTML][HTML] Surgery, with or without tamoxifen, vs tamoxifen alone for older women with operable breast cancer: Cochrane review

D Hind, L Wyld, MW Reed - British Journal of cancer, 2007 - nature.com
The published literature comparing surgery, with or without adjuvant endocrine therapy, with
endocrine therapy alone in older women with operable breast cancer was systematically …

Undertreatment strongly decreases prognosis of breast cancer in elderly women

C Bouchardy, E Rapiti, G Fioretta, P Laissue… - Journal of clinical …, 2003 - ascopubs.org
Purpose: No consensus exists on therapy of elderly cancer patients. Treatments are
influenced by unclear standards and are usually less aggressive. This study aims to …

Breast carcinoma in elderly women: features of disease presentation, choice of local and systemic treatments compared with younger postmenopausal patients

R Gennari, G Curigliano, N Rotmensz… - … Journal of the …, 2004 - Wiley Online Library
BACKGROUND Aging remains one of the single greatest risk factors for the development of
new breast carcinoma. The aim of the study was to evaluate the relation between biologic …

[HTML][HTML] Axillary dissection versus no axillary dissection in elderly patients with breast cancer and no palpable axillary nodes: results after 15 years of follow-up

G Martelli, R Miceli, MG Daidone, G Vetrella… - Annals of surgical …, 2011 - Springer
Objective To assess the long-term safety of no axillary clearance in elderly patients with
breast cancer and nonpalpable axillary nodes. Background Lymph node evaluation in …

Surgery versus primary endocrine therapy for operable primary breast cancer in elderly women (70 years plus)

D Hind, L Wyld, C Beverley… - Cochrane Database of …, 2006 - cochranelibrary.com
Background Several studies have evaluated the clinical effectiveness of endocrine therapy
alone in women aged 70 years or over and who are fit for surgery. Objectives To identify and …

[HTML][HTML] Long-term outcomes of ductal carcinoma in situ of the breast: a systematic review, meta-analysis and meta-regression analysis

KE Stuart, N Houssami, R Taylor, A Hayen, J Boyages - BMC cancer, 2015 - Springer
Background To summarize data on long-term ipsilateral local recurrence (LR) and breast
cancer death rate (BCDR) for patients with ductal carcinoma in situ (DCIS) who received …

Late follow-up of a randomized trial of surgery plus tamoxifen versus tamoxifen alone in women aged over 70 years with operable breast cancer

M Fennessy, T Bates, K MacRae, D Riley… - Journal of British …, 2004 - academic.oup.com
Background Breast cancer has been considered a more indolent disease in the elderly, who
are less tolerant of aggressive therapy. This trial tested the hypothesis that tamoxifen without …

Feasibility of magnetic resonance imaging–guided focused ultrasound surgery as an adjunct to tamoxifen therapy in high-risk surgical patients with breast carcinoma

D Gianfelice, A Khiat, Y Boulanger, M Amara… - Journal of Vascular and …, 2003 - Elsevier
PURPOSE: To evaluate the feasibility of treating breast neoplasms with use of magnetic
resonance (MR) imaging–guided focused ultrasound (US) surgery. MATERIALS AND …

[HTML][HTML] Stage and treatment variation with age in postmenopausal women with breast cancer: compliance with guidelines

L Wyld, DK Garg, ID Kumar, H Brown… - British journal of …, 2004 - nature.com
Breast cancer-specific mortality is static in older women despite having fallen in younger age
groups, possibly due to lack of screening and differences in treatment. This study compared …