Considering sex as a biological variable in basic and clinical studies: an endocrine society scientific statement

A Bhargava, AP Arnold, DA Bangasser… - Endocrine …, 2021 - academic.oup.com
Abstract In May 2014, the National Institutes of Health (NIH) stated its intent to “require
applicants to consider sex as a biological variable (SABV) in the design and analysis of NIH …

Nutrition in menopausal women: a narrative review

TR Silva, K Oppermann, FM Reis, PM Spritzer - Nutrients, 2021 - mdpi.com
Among the various aspects of health promotion and lifestyle adaptation to the
postmenopausal period, nutritional habits are essential because they concern all women …

Immunological and metabolic causes of infertility in polycystic ovary syndrome

AM Kicińska, RB Maksym, MA Zabielska-Kaczorowska… - Biomedicines, 2023 - mdpi.com
Infertility has been recognized as a civilizational disease. One of the most common causes
of infertility is polycystic ovary syndrome (PCOS). Closely interrelated immunometabolic …

Sex hormones regulate metainflammation in diet-induced obesity in mice

M Varghese, C Griffin, S Abrishami, L Eter… - Journal of Biological …, 2021 - ASBMB
Men have a statistically higher risk of metabolic and cardiovascular disease than
premenopausal women, but the mechanisms mediating these differences are elusive …

[HTML][HTML] Ketogenic diet as a potential intervention for lipedema

L Keith, CA Seo, C Rowsemitt, M Pfeffer, M Wahi… - Medical hypotheses, 2021 - Elsevier
Lipedema (LI) is a common yet misdiagnosed condition, often misconstrued with obesity. LI
affects women almost exclusively, and its painful and life-changing symptoms have long …

Estrobolome dysregulation is associated with altered immunometabolism in a mouse model of endometriosis

H Alghetaa, A Mohammed, NP Singh… - Frontiers in …, 2023 - frontiersin.org
Introduction Endometriosis is a painful disease that affects around 5% of women of
reproductive age. In endometriosis, ectopic endometrial cells or seeded endometrial debris …

Recent update on the molecular mechanisms of gonadal steroids action in adipose tissue

A Wawrzkiewicz-Jałowiecka, A Lalik… - International Journal of …, 2021 - mdpi.com
The gonadal steroids, including androgens, estrogens and progestogens, are involved in
the control of body fat distribution in humans. Nevertheless, not only the size and localization …

Non-alcoholic fatty liver disease: a multi-system disease influenced by ageing and sex, and affected by adipose tissue and intestinal function

J Bilson, JK Sethi, CD Byrne - Proceedings of the Nutrition Society, 2022 - cambridge.org
In recent years, a wealth of factors are associated with increased risk of developing non-
alcoholic fatty liver disease (NAFLD) and NAFLD is now thought to increase the risk of …

Impacts of immunometabolism on male reproduction

L Ye, W Huang, S Liu, S Cai, L Hong, W Xiao… - Frontiers in …, 2021 - frontiersin.org
The physiological process of male reproduction relies on the orchestration of
neuroendocrine, immune, and energy metabolism. Spermatogenesis is controlled by the …

Cutting edge: the regulatory mechanisms of macrophage polarization and function during pregnancy

LL Wang, ZH Li, H Wang, J Kwak-Kim… - Journal of reproductive …, 2022 - Elsevier
Macrophages are highly diverse cells and represent the major antigen-presenting cell at the
maternal-fetal interface. Except for protecting the embryo with half of the paternal antigens …