[HTML][HTML] Growth hormone and insulin-like growth factor action in reproductive tissues

E Ipsa, VF Cruzat, JN Kagize, JL Yovich… - Frontiers in …, 2019 - frontiersin.org
The role of growth hormone (GH) in human fertility is widely debated with some studies
demonstrating improvements in oocyte yield, enhanced embryo quality, and in some cases …

Molecular mechanisms underlying the activation of mammalian primordial follicles

D Adhikari, K Liu - Endocrine reviews, 2009 - academic.oup.com
In humans and other mammalian species, the pool of resting primordial follicles serves as
the source of developing follicles and fertilizable ova for the entire length of female …

Cellular and molecular regulation of the activation of mammalian primordial follicles: somatic cells initiate follicle activation in adulthood

H Zhang, K Liu - Human reproduction update, 2015 - academic.oup.com
BACKGROUND The first small follicles to appear in the mammalian ovaries are primordial
follicles. The initial pool of primordial follicles serves as the source of developing follicles …

The growth hormone receptor: mechanism of activation and clinical implications

AJ Brooks, MJ Waters - Nature Reviews Endocrinology, 2010 - nature.com
Growth hormone is widely used clinically to promote growth and anabolism and for other
purposes. Its actions are mediated via the growth hormone receptor, both directly by tyrosine …

[HTML][HTML] The role of growth hormone on ovarian functioning and ovarian angiogenesis

J Devesa, D Caicedo - Frontiers in endocrinology, 2019 - frontiersin.org
Although not yet well-understood, today it is clear that Growth Hormone (GH) exerts a
relevant role in the regulation of ovulation and fertility; in fact, fertility is lower in women with …

Multiple effects of growth hormone in the body: is it really the hormone for growth?

J Devesa, C Almengló… - Clinical Medicine Insights …, 2016 - journals.sagepub.com
In this review, we analyze the effects of growth hormone on a number of tissues and organs
and its putative role in the longitudinal growth of an organism. We conclude that the …

Involvement of growth hormone (GH) and insulin-like growth factor (IGF) system in ovarian folliculogenesis

JRV Silva, JR Figueiredo, R Van den Hurk - Theriogenology, 2009 - Elsevier
During the last decade, involvement of growth hormone (GH), insulin-like growth factors
(IGFs) and IGF binding proteins (IGFBPs) in ovarian folliculogenesis has been extensively …

Growth hormone and reproduction: a review of endocrine and autocrine/paracrine interactions

KL Hull, S Harvey - International journal of endocrinology, 2014 - Wiley Online Library
The somatotropic axis, consisting of growth hormone (GH), hepatic insulin‐like growth factor
I (IGF‐I), and assorted releasing factors, regulates growth and body composition …

[HTML][HTML] Growth hormone in fertility and infertility: Mechanisms of action and clinical applications

CW Chang, YW Sung, YW Hsueh, YY Chen… - Frontiers in …, 2022 - frontiersin.org
Secreted by the anterior pituitary gland, growth hormone (GH) is a peptide that plays a
critical role in regulating cell growth, development, and metabolism in multiple targeted …

The hormonal action of IGF1 in postnatal mouse growth

E Stratikopoulos, M Szabolcs… - Proceedings of the …, 2008 - National Acad Sciences
The mammalian insulin-like growth factor 1 (IGF1), which is a member of a major growth-
promoting signaling system, is produced by many tissues and functions throughout …