Understanding factors that contribute to the escalation of alcohol consumption is key to
understanding how an individual transitions from non/social drinking to AUD and to …

Background: Plasma proteins are critical mediators of cardiovascular processes and are the
targets of many drugs. Previous efforts to characterize the genetic architecture of the plasma …

Importance Alcohol genome-wide association studies (GWASs) have generally focused on
alcohol consumption and alcohol use disorder (AUD); few have examined habitual drinking …

To investigate assortative mating (AM), participation bias and socioeconomic status (SES)
with respect to the genetics of behavioural and psychiatric traits, we estimated AM …

Alcohol use is influenced by genetic and environmental factors. We examined the interactive
effects between genome-wide polygenic risk scores for alcohol use (alc-PRS) and social …

Abstract Background Individuals with South Asian ancestry have higher risk of heart disease
than other groups in Western countries; however, most genetic research has focused on …

Objective Alcohol use during emerging adulthood is associated with adverse life outcomes,
but its risk factors are not well known. Here, we predicted alcohol use in 3153 young adults …

Background A strong predictor for the development of alcohol use disorder (AUD) is altered
sensitivity to the intoxicating effects of alcohol. Individual differences in the initial sensitivity …

Históricamente, los estudios de asociación de genoma completo (GWAS) de enfermedades
psiquiátricas incluyen principalmente poblaciones europeas, excluyendo a otras, como la …

Genome-wide association studies (GWAS) of psychiatric disorders have focused primarily
on individuals of European ancestry, excluding other ancestries, including Latin American …