The pathogenesis of sepsis and potential therapeutic targets

M Huang, S Cai, J Su - International journal of molecular sciences, 2019 - mdpi.com
Sepsis is defined as “a life-threatening organ dysfunction caused by a host's dysfunctional
response to infection”. Although the treatment of sepsis has developed rapidly in the past …

Selected biomarkers correlate with the origin and severity of sepsis

M Holub, O Džupová, M Růžková… - Mediators of …, 2018 - Wiley Online Library
The microbial etiology and source of sepsis influence the inflammatory response. Therefore,
the plasma levels of cytokines (IL‐6, IL‐8, and IL‐10), chemokines (CCL2/MCP‐1, MIP‐1β) …

Changes in chemokine and growth factor levels may be useful biomarkers for monitoring disease severity in COVID-19 patients; a pilot study

B Wolszczak-Biedrzycka, J Dorf… - Frontiers in …, 2024 - frontiersin.org
Aim The aim of the present study was to assess differences in the serum levels of
chemokines and growth factors (GFs) between COVID-19 patients and healthy controls. The …

Cerebrospinal fluid chemokine patterns in children with enterovirus 71-related encephalitis

J Liu, S Li, C Cai, Y Xu, Y Jiang, Z Chen - Scientific reports, 2018 - nature.com
Abstract Enterovirus 71 (EV71) is a major pathogen that causes hand, foot and mouth
disease (HFMD) as well as neurological complications, such as encephalitis. The …

Acetylsalicylic acid differentially limits the activation and expression of cell death markers in human platelets exposed to Staphylococcus aureus strains

A Chabert, P Damien, PO Verhoeven, F Grattard… - Scientific Reports, 2017 - nature.com
Beyond their hemostatic functions, platelets alter their inflammatory response according to
the bacterial stimulus. Staphylococcus aureus is associated with exacerbated inflammation …

One Hundred Consecutive Neutropenic Febrile Episodes Demonstrate That CXCR3 Ligands Have Predictive Value in Discriminating the Severity of Infection in …

M Nowak, K Bobeff, J Walenciak, J Kołodrubiec… - Children, 2022 - mdpi.com
This study assesses the value of the CXCR3 ligands CXCL9/MIG, CXCL10/IP-10 and
CXCL11/I-TAC when used to supplement the standard infection markers C-reactive protein …

Chemokines and chemokine receptors

NM Elemam, BA Khalil… - … of Infection and …, 2022 - nchr.elsevierpure.com
Chemokines are soluble mediators that are expressed on immune and non-immune cells in
various species, and are critical for their survival and homeostasis. They are key players in …

[PDF][PDF] Blanka Wolszczak-Biedrzycka1, Justyna Dorf2, Marzena Wojewodzka-Zelezniakowicz3, Małgorzata Zendzian-Piotrowska4, Violetta Dymicka-Piekarska2 …

M Wojewódzka-Zelezniakowicz - 2024 - ppm.umb.edu.pl
Aim: The aim of the present study was to assess differences in the serum levels of
chemokines and growth factors (GFs) between COVID-19 patients and healthy controls. The …

Evaluation of diagnostic tests for HIV detection in children in Malawi

M Nyirenda Nyang'Wa - 2023 - discovery.ucl.ac.uk
Annually> 40,000 Malawian babies are exposed to HIV, and> 1800 get infected. Maternal
antibodies limit the utility of HIV antibody testing in children< 18 months, and HIV-DNA-PCR …

Pathogenesis of Crimean-Congo Haemorrhagic Fever (CCHF)-interaction of immune response, viral load and clinical course

T Fletcher - 2019 - archive.lstmed.ac.uk
Introduction Crimean-Congo haemorrhagic fever a potentially fatal acute viral disease that is
geographically widespread across southern areas of Africa and Eastern Europe, Russia and …