Non-coding RNA and diabetic kidney disease

H Ren, Q Wang - DNA and Cell Biology, 2021 - liebertpub.com
Diabetic kidney disease (DKD) is one of the most common chronic microvascular
complications of diabetes. In addition to the characteristic clinical manifestations of …

New insights into the role of HNF-1β in kidney (patho) physiology

S Ferrè, P Igarashi - Pediatric Nephrology, 2019 - Springer
Hepatocyte nuclear factor-1β (HNF-1β) is an essential transcription factor that regulates the
development and function of epithelia in the kidney, liver, pancreas, and genitourinary tract …

An endoplasmic reticulum stress-regulated lncRNA hosting a microRNA megacluster induces early features of diabetic nephropathy

M Kato, M Wang, Z Chen, K Bhatt, HJ Oh… - Nature …, 2016 - nature.com
It is important to find better treatments for diabetic nephropathy (DN), a debilitating renal
complication. Targeting early features of DN, including renal extracellular matrix …

lncRNA functional networks in oligodendrocytes reveal stage-specific myelination control by an lncOL1/Suz12 complex in the CNS

D He, J Wang, Y Lu, Y Deng, C Zhao, L Xu, Y Chen… - Neuron, 2017 - cell.com
Long noncoding RNAs (lncRNAs) are emerging as important regulators of cellular functions,
but their roles in oligodendrocyte myelination remain undefined. Through de novo …

A novel long non-coding RNA CYP4B1-PS1-001 regulates proliferation and fibrosis in diabetic nephropathy

M Wang, S Wang, D Yao, Q Yan, W Lu - Molecular and cellular …, 2016 - Elsevier
Diabetic nephropathy is an important microvascular complication of diabetes, and the
incidence of end-stage renal disease caused by it are rising annually. Long non-coding …

DNMT1 recruited by EZH2-mediated silencing of miR-484 contributes to the malignancy of cervical cancer cells through MMP14 and HNF1A

Y Hu, F Wu, Y Liu, Q Zhao, H Tang - Clinical epigenetics, 2019 - Springer
Background Emerging evidence indicates that dysregulation of microRNAs (miRNAs)
contributes to cervical cancer (CC) tumorigenesis and development. Previous work showed …

Emerging role of miRNAs in renal fibrosis

Y Fan, H Chen, Z Huang, H Zheng, J Zhou - RNA biology, 2020 - Taylor & Francis
As one type of the most common endogenous short noncoding RNAs (ncRNAs), microRNAs
(miRNAs) act as posttranscriptional regulators of gene expression and have great potential …

Mechanism of fibrosis in HNF1B-related autosomal dominant tubulointerstitial kidney disease

SC Chan, Y Zhang, A Shao, S Avdulov… - Journal of the …, 2018 - journals.lww.com
Background Mutation of HNF1B, the gene encoding transcription factor HNF-1β, is one
cause of autosomal dominant tubulointerstitial kidney disease, a syndrome characterized by …

The functions of microRNA-200 family in ovarian cancer: beyond epithelial-mesenchymal transition

PW Choi, SW Ng - International journal of molecular sciences, 2017 - mdpi.com
The majority of studies on microRNA-200 family members (miR-200s) in human cancers are
based on the premise that miR-200s maintain epithelial cell integrity by suppressing …

HOXD‐AS1/miR‐130a sponge regulates glioma development by targeting E2F8.

Y Chen, F Zhao, D Cui, R Jiang… - … journal of cancer, 2018 - search.ebscohost.com
Glioma development is an extremely complex process with changes occurring in numerous
genes. HOXD antisense growth‐associated long noncoding RNA (HOXD‐AS1), an …