Epitope-based vaccine design: a comprehensive overview of bioinformatics approaches
Highlights•Epitope vaccines provide maximal therapeutic efficacy with minimal side
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
effects.•Reverse vaccinology can be used for designing epitope vaccines.•Computational …
Immunoinformatics and vaccine development: an overview
AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …
saved several lives, reduced treatment costs and raised the quality of animal and human …
Identification of Putative Vaccine and Drug Targets against the Methicillin-Resistant Staphylococcus aureus by Reverse Vaccinology and Subtractive Genomics …
Methicillin-resistant Staphylococcus aureus (MRSA) is an opportunistic pathogen and
responsible for causing life-threatening infections. The emergence of hypervirulent and …
responsible for causing life-threatening infections. The emergence of hypervirulent and …
Subtractive genomics profiling for potential drug targets identification against Moraxella catarrhalis
Moraxella catarrhalis (M. catarrhalis) is a gram-negative bacterium, responsible for major
respiratory tract and middle ear infection in infants and adults. The recent emergence of the …
respiratory tract and middle ear infection in infants and adults. The recent emergence of the …
Immunoinformatics and Molecular Docking Studies Predicted Potential Multiepitope‐Based Peptide Vaccine and Novel Compounds against Novel SARS‐CoV‐2 …
Background. Coronaviruses (CoVs) are enveloped positive‐strand RNA viruses which have
club‐like spikes at the surface with a unique replication process. Coronaviruses are …
club‐like spikes at the surface with a unique replication process. Coronaviruses are …
Identification of core therapeutic targets for Monkeypox virus and repurposing potential of drugs against them: An in silico approach
Monkeypox virus (mpox virus) outbreak has rapidly spread to 82 non-endemic countries.
Although it primarily causes skin lesions, secondary complications and high mortality (1 …
Although it primarily causes skin lesions, secondary complications and high mortality (1 …
Elucidation of novel compounds and epitope-based peptide vaccine design against C30 endopeptidase regions of SARS-CoV-2 using immunoinformatics …
S Marriam, MS Afghan, M Nadeem, M Sajid… - Frontiers in Cellular …, 2023 - frontiersin.org
There has been progressive improvement in immunoinformatics approaches for epitope-
based peptide design. Computational-based immune-informatics approaches were applied …
based peptide design. Computational-based immune-informatics approaches were applied …
Computational Design of a Chimeric Vaccine against Plesiomonas shigelloides Using Pan-Genome and Reverse Vaccinology
M Mushtaq, S Khan, M Hassan, AI Al-Harbi… - Vaccines, 2022 - mdpi.com
The swift emergence of antibiotic resistance (AR) in bacterial pathogens to make themselves
adaptable to changing environments has become an alarming health issue. To prevent AR …
adaptable to changing environments has become an alarming health issue. To prevent AR …
Identification of a Novel Therapeutic Target against XDR Salmonella Typhi H58 Using Genomics Driven Approach Followed Up by Natural Products Virtual Screening
Typhoid fever is caused by a pathogenic, rod-shaped, flagellated, and Gram-negative
bacterium known as Salmonella Typhi. It features a polysaccharide capsule that acts as a …
bacterium known as Salmonella Typhi. It features a polysaccharide capsule that acts as a …
Identification of repurposable drug targets in Mycoplasma pneumoniae using subtractive genomics, molecular docking and dynamics simulation
Mycoplasma pneumoniae is a significant causative agent of community-acquired
pneumonia, causing acute inflammation in the upper and lower respiratory tract as well as …
pneumonia, causing acute inflammation in the upper and lower respiratory tract as well as …