Controlling protein adsorption through nanostructured polymeric surfaces

I Firkowska‐Boden, X Zhang… - Advanced healthcare …, 2018 - Wiley Online Library
The initial host response to healthcare materials' surfaces after implantation is the
adsorption of proteins from blood and interstitial fluids. This adsorbed protein layer …

A bottom-up approach to understanding protein layer formation at solid–liquid interfaces

M Kastantin, BB Langdon, DK Schwartz - Advances in colloid and interface …, 2014 - Elsevier
A common goal across different fields (eg separations, biosensors, biomaterials,
pharmaceuticals) is to understand how protein behavior at solid–liquid interfaces is affected …

How nanotopography-induced conformational changes of fibrinogen affect platelet adhesion and activation

I Firkowska-Boden, C Helbing, TJ Dauben, M Pieper… - Langmuir, 2020 - ACS Publications
The conformational state of adsorbed human plasma fibrinogen (HPF) has been recognized
as the determinant factor in platelet adhesion and thrombus formation on blood-contacting …

Protein–polymer interaction characteristics unique to nanoscale interfaces: A perspective on recent insights

DH Cho, J Hahm - The Journal of Physical Chemistry B, 2021 - ACS Publications
Protein interactions at polymer interfaces represent a complex but ubiquitous phenomenon
that demands an entirely different focus of investigation than what has been attempted …

Identifying mechanisms of interfacial dynamics using single-molecule tracking

M Kastantin, R Walder, DK Schwartz - Langmuir, 2012 - ACS Publications
The “soft”(ie, noncovalent) interactions between molecules and surfaces are complex and
highly varied (eg, hydrophobic, hydrogen bonding, and ionic), often leading to …

Nanopatterning effects on astrocyte reactivity

ES Ereifej, HW Matthew, G Newaz… - … Research Part A, 2013 - Wiley Online Library
An array of design strategies have been targeted toward minimizing failure of implanted
microelectrodes by minimizing the chronic glial scar around the microelectrode under …

Distinct adsorption configurations and self-assembly characteristics of fibrinogen on chemically uniform and alternating surfaces including block copolymer …

S Song, K Ravensbergen, A Alabanza, D Soldin… - ACS …, 2014 - ACS Publications
Understanding protein–surface interactions is crucial to solid-state biomedical applications
whose functionality is directly correlated with the precise control of the adsorption …

[PDF][PDF] Adsorption of multimeric T cell antigens on carbon nanotubes: effect on protein structure and antigen-specific T cell stimulation

TR Fadel, N Li, S Shah, M Look, LD Pfefferle, GL Haller… - Small, 2013 - academia.edu
Carbon nanotubes (CNTs) have shown great potential for applications in biosensing,[1]
diagnostics,[2] and drug delivery.[3] Due to their unique physio-chemical properties, they …

Recent advances towards single biomolecule level understanding of protein adsorption phenomena unique to nanoscale polymer surfaces with chemical variations

DH Cho, T Xie, J Truong, AC Stoner, J Hahm - Nano Research, 2020 - Springer
Protein adsorption onto polymer surfaces is a very complex and ubiquitous phenomenon
whose integrated process impacts essential applications in our daily lives such as food …

Biomaterial nanotopography-mediated cell responses: experiment and modeling

L Yang, H Liu, Y Lin - International Journal of Smart and Nano …, 2014 - Taylor & Francis
The rapid development of fabrication and processing technologies in the past two decades
has enabled researchers to introduce nanoscale features into materials which, interestingly …