HIV-1-associated neurocognitive disorder: epidemiology, pathogenesis, diagnosis, and treatment

C Eggers, G Arendt, K Hahn, IW Husstedt… - Journal of …, 2017 - Springer
The modern antiretroviral treatment of human immunodeficiency virus (HIV-1) infection has
considerably lowered the incidence of opportunistic infections. With the exception of the …

Cognitive disorders in people living with HIV

A Winston, S Spudich - The Lancet HIV, 2020 - thelancet.com
High rates of cognitive disorders in antiretroviral-treated people living with HIV have been
described worldwide. The exact prevalence of such cognitive disorders is determined by the …

Updated research nosology for HIV-associated neurocognitive disorders

A Antinori, G Arendt, JT Becker, BJ Brew, DA Byrd… - Neurology, 2007 - AAN Enterprises
In 1991, the AIDS Task Force of the American Academy of Neurology published
nomenclature and research case definitions to guide the diagnosis of neurologic …

Pathways to neuronal injury and apoptosis in HIV-associated dementia

M Kaul, GA Garden, SA Lipton - Nature, 2001 - nature.com
Abstract Human immunodeficiency virus-1 (HIV-1) can induce dementia with alarming
occurrence worldwide. The mechanism remains poorly understood, but discovery in brain of …

Prevalence of nonconvulsive status epilepticus in comatose patients

AR Towne, EJ Waterhouse, JG Boggs, LK Garnett… - Neurology, 2000 - AAN Enterprises
Background: Nonconvulsive status epilepticus (NCSE) is a form of status epilepticus (SE)
that is an often unrecognized cause of coma. Objective: To evaluate the presence of NCSE …

HIV and antiretroviral therapy in the brain: neuronal injury and repair

R Ellis, D Langford, E Masliah - Nature Reviews Neuroscience, 2007 - nature.com
Approximately 40 million people worldwide are infected with human immunodeficiency virus
(HIV). Despite HIV's known propensity to infect the CNS and cause neurological disease …

Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment

J Harezlak, S Buchthal, M Taylor, G Schifitto, J Zhong… - Aids, 2011 - journals.lww.com
Objective: To determine whether cognitive impairment and brain injury as measured by
proton magnetic resonance spectroscopy (MRS) persist in the setting of HAART. Design …

HIV-associated neurologic disease incidence changes: Multicenter AIDS Cohort Study, 1990–1998

N Sacktor, RH Lyles, R Skolasky, C Kleeberger… - Neurology, 2001 - AAN Enterprises
This study examined the temporal trends in the incidence rates of HIV dementia,
cryptococcal meningitis, toxoplasmosis, progressive multifocal leukoencephalopathy, and …

Cognitive impairment in patients with AIDS–prevalence and severity

CC Watkins, GJ Treisman - HIV/AIDS-Research and Palliative Care, 2015 - Taylor & Francis
The advent of highly active antiretroviral therapy has prolonged the life expectancy of HIV
patients and decreased the number of adults who progress to AIDS and HIV-associated …

Methamphetamine dependence increases risk of neuropsychological impairment in HIV infected persons

JD Rippeth, RK Heaton, CL Carey… - Journal of the …, 2004 - cambridge.org
Both HIV infection and methamphetamine dependence can be associated with brain
dysfunction. Little is known, however, about the cognitive effects of concurrent HIV infection …