[HTML][HTML] Novel drug targets and molecular mechanisms for sarcopenia based on systems biology

AB Ceyhan, M Ozcan, W Kim, X Li, O Altay… - Biomedicine & …, 2024 - Elsevier
Sarcopenia is a major public health concern among older adults, leading to disabilities, falls,
fractures, and mortality. This study aimed to elucidate the pathophysiological mechanisms of …

Aging represses lung tumorigenesis and alters tumor suppression

EG Shuldiner, S Karmakar, MK Tsai, JD Hebert… - bioRxiv, 2024 - biorxiv.org
Most cancers are diagnosed in persons over the age of sixty, but little is known about how
age impacts tumorigenesis. While aging is accompanied by mutation accumulation-widely …