Nitric oxide (NO) signalling has pleiotropic roles in biology and a crucial function in
cardiovascular homeostasis. Tremendous knowledge has been accumulated on the …

Research into cardiac autonomic control has received great interest in the past 20 years,
and we are now at a critical juncture with regard to the clinical translation of the experimental …

The cardiac autonomic nervous system (CANS) plays a key role for the regulation of cardiac
activity with its dysregulation being involved in various heart diseases, such as cardiac …

There is continuing belief that cardiac parasympathetic postganglionic fibres are sparse or
absent from the ventricles. This review of the literature shows that the supposition is a myth …

Unanticipated, novel hypothesis on nitric oxide (NO) radical, an inorganic, labile, gaseous
molecule, as a neurotransmitter first appeared in late 1989 and into the early 1990s, and …

The role of the autonomic nervous system. The mechanisms by which physical training
exerts its beneficial effects on mortality and cardiovascular disease are surprisingly ill …

The nervous system and cardiovascular system develop in concert and are functionally
interconnected in both health and disease. This white paper focuses on the cellular and …

Dysfunction of the intrinsic cardiac nervous system is implicated in the genesis of atrial and
ventricular arrhythmias. While this system has been studied extensively in animal models …

Classical physiology teaches that vagal post-ganglionic nerves modulate the heart via
acetylcholine acting at muscarinic receptors, whilst it is accepted that vagus nerve …

1 We tested the hypothesis that nitric oxide (NO) augments vagal neurotransmission and
bradycardia via phosphorylation of presynaptic calcium channels to increase vesicular …