Light: a magical tool for controlled drug delivery

Y Tao, HF Chan, B Shi, M Li… - Advanced Functional …, 2020 - Wiley Online Library
Light is a particularly appealing tool for on‐demand drug delivery due to its noninvasive
nature, ease of application, and exquisite temporal and spatial control. Great progress is …

Smart materials for drug delivery and cancer therapy

Y Yang, W Zeng, P Huang, X Zeng, L Mei - View, 2021 - Wiley Online Library
Until now, enormous smart materials have been engineered with endogenous stimulators
such as pH, reactive oxygen species, glutathione, hypoxia and enzyme, or exogenous …

Targeting drug delivery with light: A highly focused approach

TL Rapp, CA DeForest - Advanced drug delivery reviews, 2021 - Elsevier
Light is a uniquely powerful tool for controlling molecular events in biology. No other
external input (eg, heat, ultrasound, magnetic field) can be so tightly focused or so highly …

Controllable hypoxia-activated chemotherapy as a dual enhancer for synergistic cancer photodynamic immunotherapy

M Wang, M He, M Zhang, S Xue, T Xu, Y Zhao, D Li… - Biomaterials, 2023 - Elsevier
The efficacy of photodynamic therapy (PDT) is severely limited by the hypoxic tumor
microenvironment (TME), while the performance of PDT-aroused antitumor immunity is …

[HTML][HTML] Near-infrared photoresponsive drug delivery nanosystems for cancer photo-chemotherapy

X Wang, Z Xuan, X Zhu, H Sun, J Li, Z Xie - Journal of nanobiotechnology, 2020 - Springer
Drug delivery systems (DDSs) based on nanomaterials have shown a promise for cancer
chemotherapy; however, it remains a great challenge to localize on-demand release of …

Photodynamic‐chemodynamic cascade reactions for efficient drug delivery and enhanced combination therapy

S Wang, G Yu, W Yang, Z Wang, O Jacobson… - Advanced …, 2021 - Wiley Online Library
Nanomedicines with photodynamic therapy and reactive oxygen species (ROS)‐triggered
drug release capabilities are promising for cancer therapy. However, most of the …

Reactive oxygen species-upregulating nanomedicines towards enhanced cancer therapy

Y Ding, Q Pan, W Gao, Y Pu, K Luo, B He - Biomaterials Science, 2023 - pubs.rsc.org
Reactive oxygen species (ROS) play a crucial role in physiological and pathological
processes, emerging as a therapeutic target in cancer. Owing to the high concentration of …

[HTML][HTML] Utilization of polymer-lipid hybrid nanoparticles for targeted anti-cancer therapy

A Mohanty, S Uthaman, IK Park - Molecules, 2020 - mdpi.com
Cancer represents one of the most dangerous diseases, with 1.8 million deaths worldwide.
Despite remarkable advances in conventional therapies, these treatments are not effective …

[HTML][HTML] Recent advances in nanomicelles delivery systems

SM Tawfik, S Azizov, MR Elmasry, M Sharipov, YI Lee - Nanomaterials, 2020 - mdpi.com
The efficient and selective delivery of therapeutic drugs to the target site remains the main
obstacle in the development of new drugs and therapeutic interventions. Up until today …

[HTML][HTML] Current limitations and recent progress in nanomedicine for clinically available photodynamic therapy

J Park, YK Lee, IK Park, SR Hwang - Biomedicines, 2021 - mdpi.com
Photodynamic therapy (PDT) using oxygen, light, and photosensitizers has been receiving
great attention, because it has potential for making up for the weakness of the existing …