The ability of the brain to store and process information relies on changing the strength of
connections between neurons. Synaptic facilitation is a form of short-term plasticity that …

Most neuronal communication relies upon the synchronous release of neurotransmitters,
which occurs through synaptic vesicle exocytosis triggered by action potential invasion of a …

Synaptotagmin, complexin, and neuronal SNARE (soluble N-ethylmaleimide sensitive factor
attachment protein receptor) proteins mediate evoked synchronous neurotransmitter …

It has been known for more than 70 years that synaptic strength is dynamically regulated in a
use-dependent manner. At synapses with a low initial release probability, closely spaced …

Synaptotagmin-1 and neuronal SNARE proteins have central roles in evoked synchronous
neurotransmitter release; however, it is unknown how they cooperate to trigger synaptic …

In forebrain neurons, knockout of synaptotagmin-1 blocks fast Ca 2+-triggered synchronous
neurotransmitter release but enables manifestation of slow Ca 2+-triggered asynchronous …

Strengthening of synaptic connections by NMDA (N-methyl-d-aspartate) receptor-dependent
long-term potentiation (LTP) shapes neural circuits and mediates learning and memory …

This review summarizes current knowledge of synaptic proteins that are central to synaptic
vesicle fusion in presynaptic active zones, including SNAREs (s oluble N-ethylmaleimide …

The article presents a lecture on the molecular machinery of synaptic neurotransmitter
release. It discusses the speed of synaptic transmission of neurotransmitters, the molecular …

Synaptic neurotransmitter release is mediated by an orchestra of presynaptic proteins that
precisely control and trigger fusion between synaptic vesicles and the neuron terminal at the …