The vast interindividual clinical variability observed in any microbial infection—ranging from
silent infection to lethal disease—is increasingly being explained by human genetic and …

Talaromycosis is an invasive mycosis endemic in tropical and subtropical Asia and is
caused by the pathogenic fungus Talaromyces marneffei. Approximately 17,300 cases of T …

Background Autoantibodies against interferon-γ are associated with severe disseminated
opportunistic infection, but their importance and prevalence are unknown. Methods We …

Talaromyces (Penicillium) marneffei is an important pathogenic thermally dimorphic fungus
causing systemic mycosis in Southeast Asia. The clinical significance of T. marneffei …

Non-tuberculous mycobacteria cause a broad range of clinical disorders, from cutaneous
infections, such as cervical or intrathoracic lymphadenitis in children, to disseminated …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (M. tb) and a few related
mycobacteria, is a devastating disease, killing more than a million individuals per year …

Anticytokine autoantibodies are an emerging disease etiology, through the disturbance of
physiological functions of cognate cytokines. Anti-interferon (IFN)-γ autoantibodies (AIGAs) …

Talaromycosis (penicilliosis) is a major fungal disease endemic across a narrow band of
tropical countries of South and Southeast Asia. The etiologic agent is a thermally dimorphic …

Talaromyces marneffei causes life-threatening opportunistic infections, mainly in Southeast
Asia and South China. T. marneffei mainly infects patients with human immunodeficiency …

The most important remaining gap in our knowledge is probably an understanding of how
NTS is transmitted, and the nature of the relationship between diarrhoeal disease, carriage …