The physics of respiratory particle generation, fate in the air, and inhalation

L Morawska, G Buonanno, A Mikszewski… - Nature Reviews …, 2022 - nature.com
Given that breathing is one of the most fundamental physiological functions, there is an
urgent need to broaden our understanding of the fluid dynamics that governs it. There would …

[HTML][HTML] Membrane-disruptive peptides/peptidomimetics-based therapeutics: Promising systems to combat bacteria and cancer in the drug-resistant era

L Lin, J Chi, Y Yan, R Luo, X Feng, Y Zheng… - … Pharmaceutica Sinica B, 2021 - Elsevier
Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or
anticarcinogens that present a general killing mechanism through the physical disruption of …

Acoustic lung imaging utilized in continual assessment of patients with obstructed airway: A systematic review

CS Lee, M Li, Y Lou, QH Abbasi, MA Imran - Sensors, 2023 - mdpi.com
Smart respiratory therapy is enabled by continual assessment of lung functions. This
systematic review provides an overview of the suitability of equipment-to-patient acoustic …

An inhalable theranostic system for local tuberculosis treatment containing an isoniazid loaded metal organic framework Fe-MIL-101-NH2—from raw MOF to drug …

G Wyszogrodzka-Gaweł, P Dorożyński, S Giovagnoli… - Pharmaceutics, 2019 - mdpi.com
The theranostic approach to local tuberculosis treatment allows drug delivery and imaging of
the lungs for a better control and personalization of antibiotic therapy. Metal-organic …

Disposition and safety of inhaled biodegradable nanomedicines: Opportunities and challenges

S Haque, MR Whittaker, MP McIntosh… - … , Biology and Medicine, 2016 - Elsevier
The inhaled delivery of nanomedicines can provide a novel, non-invasive therapeutic
strategy for the more localised treatment of lung-resident diseases and potentially also …

Future prospect of insulin inhalation for diabetic patients: The case of Afrezza versus Exubera

MM Al-Tabakha - Journal of Controlled Release, 2015 - Elsevier
The current review was designed to compare between the insulin inhalation systems
Exubera and Afrezza and to investigate the reasons why Exubera was unsuccessful, when …

Affordable, portable and self-administrable electrical impedance tomography enables global and regional lung function assessment

F Zouari, WY Oon, D Modak, WH Lee, WC Kwok… - Scientific Reports, 2022 - nature.com
Accessibility of diagnostic screening and treatment monitoring devices for respiratory
diseases is critical in promoting healthcare and reducing sudden complications and …

Experimental methods for flow and aerosol measurements in human airways and their replicas

F Lizal, J Jedelsky, K Morgan, K Bauer, J Llop… - European Journal of …, 2018 - Elsevier
Recent developments in the prediction of local aerosol deposition in human lungs are driven
by the fast development of computational simulations. Although such simulations provide …

Lung function imaging methods in cystic fibrosis pulmonary disease

M Kołodziej, MJ de Veer, M Cholewa, GF Egan… - Respiratory …, 2017 - Springer
Monitoring of pulmonary physiology is fundamental to the clinical management of patients
with Cystic Fibrosis. The current standard clinical practise uses spirometry to assess lung …

[HTML][HTML] In vivo dynamic phase-contrast X-ray imaging using a compact light source

R Gradl, M Dierolf, B Günther, L Hehn, W Möller… - Scientific Reports, 2018 - nature.com
We describe the first dynamic and the first in vivo X-ray imaging studies successfully
performed at a laser-undulator-based compact synchrotron light source. The X-ray …