From a structural perspective, the predominant glial cell of the central nervous system, the
astrocyte, is positioned to regulate synaptic transmission and neurovascular coupling: the …

Cerebral blood flow is controlled by two crucial processes, cerebral autoregulation (CA) and
neurovascular coupling (NVC) or functional hyperemia. Whereas CA ensures constant …

The cellular mechanisms underlying functional hyperemia—the coupling of neuronal
activation to cerebral blood vessel responses—are not yet known. Here we show in rat …

The role of GABA in regulating cerebral microvessels was examined in the parenchyma of
the hippocampus and the surface of the neocortex. Microvessels were monitored in in vitro …

We have studied modulation of the slow Ca2+-activated K+ current (I sAHP) in CA1
hippocampal pyramidal neurons by three peptide transmitters: corticotropin releasing factor …

This study examined the role of glutamate receptor activation in the regulation of
microvascular tone in the hippocampus and neocortex of the rat. Microvascular and …

Calcitonin gene-related peptide (CGRP) is the main mediator of trigeminal pain signal.
Functional CGRP receptors were detected in trigeminal satellite cells, a specialized type of …

Migraine is a debilitating neurological condition that involves the neuropeptide calcitonin
gene-related peptide (CGRP). An exciting development is the recent FDA approval of the …

Neurovascular research has made significant strides toward understanding how the brain
neurovascular unit accomplishes rapid and spatial increases in blood flow following …

We investigated the effect of experimental preeclampsia on hyperemia during seizure in the
hippocampus and vascular function and structure of hippocampal arterioles using Sprague …