Background and purpose: Radiotherapy plays an essential role in early breast cancer
treatment, but is also associated with an increased risk of second malignancies decades …

An increasing number of women is surviving breast cancer and due to that at risk of
developing an isolated ipsilateral breast tumor recurrence (IBTR) or a contralateral breast …

Purpose To determine the prognostic and predictive value of intrinsic subtyping by using
immunohistochemical (IHC) biomarkers for ipsilateral breast relapse (IBR) in participants in …

Background Postoperative radiation therapy after breast conserving surgery in the older
adult population is a matter of debate; although radiation therapy was shown to benefit these …

Background Two randomized intraoperative radiation therapy trials for early-stage breast
cancer were recently published. The ELIOT Trial used electrons (IOERT), and the TARGIT-A …

Radiation therapy is a standard therapeutic option in the post-operative setting for early
breast cancer patients after breast conserving surgery, providing a substantial benefit in …

The 70-gene signature (MammaPrint™) has been developed to predict the risk of distant
metastases in breast cancer and select those patients who may benefit from adjuvant …

Purpose The study aimed to explore the role of adjuvant radiotherapy (RT) after breast-
conserving surgery (BCS) in elder women with early-stage breast cancer (BC). Methods BC …

The reduction in the burden related to treatment is becoming more and more important in
modern oncology. Radiation therapy is a mainstay option in the postoperative setting for …

Background In early breast cancer treatment, the preferred surgical regimen remains a topic
of controversy, and conventional pairwise meta-analysis cannot provide a hierarchy based …