Over the years biodegradable polymers have emerged as promising polymeric materials in
drug delivery and vaccination due to their fascinating properties like biocompatibility …

The development of novel immune adjuvants is emerging as a significant area of vaccine
delivery based on the continued necessity to amplify immune responses to a wide array of …

Numerous studies have demonstrated that chitosan and their derivatives (N-trimethyl
chitosan, mono-N-carboxymethyl chitosan) are effective and safe absorption enhancers to …

The striking advantage of mucosal vaccination is the production of local antibodies at the
sites where pathogens enter the body. Because vaccines alone are not sufficiently taken up …

BSA was entrapped in particles of different sizes (200, 500 and 1000nm) prepared from poly
(d, l-lactic-co-glycolic) acid by a double emulsion method. The particles were given, either …

Therapeutic strategies that involve the manipulation of the host's immune system are gaining
momentum in cancer research. Antigen-loaded nanocarriers are capable of being actively …

Tolerogenic vaccines are aimed at inhibiting antigen-specific immune responses. Antigen-
loaded nanoparticles (NPs) have been recently emerged as ideal tools for tolerogenic …

The development and widespread application of vaccines has been one of the most
significant achievements of modern medicine. Vaccines have not only been instrumental in …

Most pathogens initiate their infections at the human mucosal surface. Therefore, mucosal
vaccination, especially through oral or intranasal administration routes, is highly desired for …

In this study, the ability of chitosan microparticles to enhance both the systemic and local
immune responses against diphtheria toxoid (DT) after oral and nasal administration in mice …