CKD frequently leads to chronic cardiac dysfunction. This complex relationship has been
termed as cardiorenal syndrome type 4 or cardio-renal link. Despite numerous studies and …

Cardiovascular disease is one of the main causes of human mortality. Cytokines play crucial
roles in the development of cardiovascular disease. Interleukin (IL)-6 family members are a …

Recent clinical trial data suggest a cardiorenal protective effect of sodium glucose
cotransporter 2 (SGLT2) inhibition. We demonstrate that chemical denervation in neurogenic …

Chronic kidney disease (CKD) is one of the major health problems of the modern age. It
represents an important public health challenge with an ever-lasting rising prevalence …

Background and aims Malnutrition and inflammation are closely linked to vascular
calcification (VC), the severity of which correlate with adverse outcome. However, there were …

Background Chronic kidney disease (CKD) and aortic stenosis (AS) share many risk factors.
Objectives This study sought to evaluate whether kidney dysfunction is associated with the …

Chronic kidney disease is a devastating condition resulting from irreversible loss of nephron
numbers and function and leading to end-stage renal disease and mineral disorders …

Introduction: Inflammation is important in the pathogenesis of atherosclerosis. Elevated
interleukin-6 (IL-6) is associated with cardiovascular events and also predicts mortality in …

Hypertensive nephropathy (HTN) is the second leading cause of end-stage renal disease
(ESRD) and a chronic inflammatory disease. Persistent hypertension leads to lesions of …

Aortic stiffness is an independent risk factor for aortic diseases such as aortic dissection
which commonly occurred with aging and hypertension. Chemokine receptor CXCR6 is …