Sexual differentiation of malaria parasites from the asexual blood stage into gametocytes is
an essential part of the life cycle, as gametocytes are the form that is taken up by the …

Preventing human-to-mosquito transmission of malaria parasites provides possible
solutions to interrupt the malaria parasite life cycle for malaria elimination. The development …

Data-independent acquisition approaches typically rely on experiment-specific spectrum
libraries, requiring offline fractionation and tens to hundreds of injections. We demonstrate a …

INTRODUCTION Plasmodium parasites, the causative agent of malaria, are single-celled
organisms with distinct morphological developmental stages each specialized to inhabit …

Single-cell RNA-sequencing is revolutionising our understanding of seemingly
homogeneous cell populations but has not yet been widely applied to single-celled …

In the malaria parasite Plasmodium falciparum, the switch from asexual multiplication to
sexual differentiation into gametocytes is essential for transmission to mosquitos. The …

The complex life cycle of Plasmodium falciparum requires coordinated gene expression
regulation to allow host cell invasion, transmission, and immune evasion. Increasing …

Plasmodium sporozoites are transmitted from infected mosquitoes to mammals, and must
navigate the host skin and vasculature to infect the liver. This journey requires distinct …

Malaria parasites have a complex life cycle featuring diverse developmental strategies, each
uniquely adapted to navigate specific host environments. Here we use single-cell …

Our current understanding of mitochondrial functioning is largely restricted to traditional
model organisms, which only represent a fraction of eukaryotic diversity. The unusual …