Is cancer biology different in older patients?

Y Van Herck, A Feyaerts, S Alibhai… - The Lancet Healthy …, 2021 - thelancet.com
Roughly 50% of cancer cases occur in people aged 65 years or older. Older people are
often diagnosed at a later stage and might receive less (intensive) treatment, which might …

Global and regional estimates of orphans attributed to maternal cancer mortality in 2020

F Guida, R Kidman, J Ferlay, J Schüz… - Nature medicine, 2022 - nature.com
Despite women being disproportionally affected by cancer deaths at young ages, there are
no global estimates of the resulting maternal orphans, who experience health and education …

Triple-negative breast cancer prevalence in Africa: a systematic review and meta-analysis

SM Hercules, M Alnajar, C Chen, SM Mladjenovic… - BMJ open, 2022 - bmjopen.bmj.com
Objective The aggressive triple-negative breast cancer (TNBC) subtype disproportionately
affects women of African ancestry across the diaspora, but its frequency across Africa has …

[HTML][HTML] Midkine as a driver of age-related changes and increase in mammary tumorigenesis

P Yan, ER Jimenez, Z Li, T Bui, M Seehawer, J Nishida… - Cancer Cell, 2024 - cell.com
Aging is a pivotal risk factor for cancer, yet the underlying mechanisms remain poorly
defined. Here, we explore age-related changes in the rat mammary gland by single-cell …

Competitive endogenous role of the LINC00511/miR-185-3p axis and miR-301a-3p from liquid biopsy as molecular markers for breast cancer diagnosis

MM Mahmoud, EF Sanad, RAA Elshimy… - Frontiers in …, 2021 - frontiersin.org
Breast cancer (BC) is the leading cause of female cancer-related mortalities. Evidence has
illustrated the role of long non-coding RNAs (lncRNA) and microRNAs (miRNA) as …

De novo and recurrent metastatic breast cancer–A systematic review of population-level changes in survival since 1995

SJ Lord, K Bahlmann, DL O'Connell, BE Kiely… - …, 2022 - thelancet.com
Background Advances in breast cancer (BC) care have reduced mortality, but their impact
on survival once diagnosed with metastasis is less well described. This systematic review …

Out-of-pocket payment and financial risk protection for breast cancer treatment: a prospective study from India

T Wadasadawala, SK Mohanty, S Sen… - The Lancet Regional …, 2024 - thelancet.com
Background Available data on cost of cancer treatment, out-of-pocket payment and
reimbursement are limited in India. We estimated the treatment costs, out-of-pocket payment …

[HTML][HTML] Correlation between age and hormone receptor status in women with breast cancer

A Shah, G Haider, N Abro, S Bhutto, TI Baqai, S Akhtar… - Cureus, 2022 - ncbi.nlm.nih.gov
Methods A cross-sectional study was conducted at the Department of Medical Oncology,
Jinnah Postgraduate Medical Center (JPMC), Karachi, Pakistan, from January 2021 to …

Interplay of Mendelian and polygenic risk factors in Arab breast cancer patients

M Al-Jumaan, H Chu, A Alsulaiman, SY Camp, S Han… - Genome Medicine, 2023 - Springer
Background Breast cancer patients from the indigenous Arab population present much
earlier than patients from Western countries and have traditionally been underrepresented …

Prospective comparison of CT and 18F-FDG PET/MRI in N and M staging of primary breast cancer patients: Initial results

NM Bruckmann, J Kirchner, J Morawitz, L Umutlu… - PLoS …, 2021 - journals.plos.org
Objectives To compare the diagnostic accuracy of contrast-enhanced thoraco-abdominal
computed tomography and whole-body 18F-FDG PET/MRI in N and M staging in newly …