Syphilis is a fascinating and perplexing infection, with protean clinical manifestations and
both diagnostic and management ambiguities. Treponema pallidum subsp. pallidum, the …

The neglected tropical diseases represent a group of parasitic and bacterial diseases,
occurring primarily in rural areas or impoverished urban areas of developing countries …

Insights into the genomic adaptive traits of Treponema pallidum, the causative bacterium of
syphilis, have long been hampered due to the absence of in vitro culture models and the …

The antigenicity, structural location, and function of the predicted lipoprotein TP0136 of
Treponema pallidum subsp. pallidum were investigated based on previous screening …

Syphilis is a multistage disease caused by the invasive spirochete Treponema pallidum
subsp. pallidum. Despite inexpensive and effective antibiotic therapy, syphilis remains a …

High-resolution cryo electron tomography (cryo-ET) was utilized to visualize Treponema
pallidum, the causative agent of syphilis, at the molecular level. Three-dimensional (3D) …

Treponema pallidum reacts poorly with the antibodies present in rabbit and human syphilitic
sera, a property attributed to the paucity of proteins in its outer membrane. To better …

Congenital syphilis was rare in most affluent countries but there has been a slight
resurgence recently in several European countries. In large parts of the world and …

Syphilis continues to be a significant public health concern worldwide. The disease is
endemic in many low-and middle-income countries, and rates have risen sharply in high …

Syphilis, a chronic systemic sexually transmitted disease, is caused by the bacterium
Treponema pallidum (T. pallidum). Currently, syphilis remains a widespread infectious …