Triterpenoids from the genus Gynostemma: Chemistry and pharmacological activities

NH Nguyen, TKQ Ha, JL Yang, HTT Pham… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance G. pentaphyllum, also known as Jiao-Gu-Lan, has been
used traditionally as folk remedies for many diseases, including diabetes mellitus, metabolic …

Medicinal value and potential therapeutic mechanisms of Gynostemma pentaphyllum (Thunb.) Makino and its derivatives: An overview

K Li, C Ma, H Li, S Dev, JF He… - Current topics in medicinal …, 2019 - ingentaconnect.com
Gynostemma pentaphyllum (Thunb.) Makino (GpM) and its derivatives, especially
gypenosides (Gyps), are widely used as safe and convenient natural herbal drugs for the …

AMPK and metabolic disorders: the opposite roles of dietary bioactive components and food contaminants

Y Peng, Z Qi, Y Xu, X Yang, Y Cui, Q Sun - Food Chemistry, 2023 - Elsevier
AMPK is a key player in a variety of metabolic and physiological processes, which might be
considered one of the most promising targets for both prevention and treatment of metabolic …

Vibration acceleration enhances proliferation, migration, and maturation of C2C12 cells and promotes regeneration of muscle injury in male rats

S Sato, T Hanai, T Kanamoto, F Kawano… - Physiological …, 2024 - Wiley Online Library
Vibration acceleration (VA) using a whole‐body vibration device is beneficial for skeletal
muscles. However, its effect at the cellular level remains unclear. We aimed to investigate …

Dammarane-type triterpenoids from Gynostemma compressum XX Chen & DR Liang (Cucurbitaceae) and their AMPK activation effect in 3T3-L1 cells

TTT Dinh, TT Nguyen, HT Ngo, TH Tran, BV Le… - Phytochemistry, 2022 - Elsevier
Bioassay-guided fractionation of the 80% ethanol extract of Gynostemma compressum XX
Chen & DR Liang (Cucurbitaceae) resulted in the isolation and identification of eight …

Exploring the potential mechanisms of Tongmai Jiangtang capsules in treating diabetic nephropathy through multi-dimensional data

Y Liu, X Cui, X Zhang, Z Xie, W Wang, J Xi… - Frontiers in …, 2023 - frontiersin.org
Background Diabetic nephropathy (DN) is a prevalent and debilitating disease that
represents the leading cause of chronic kidney disease which imposes public health …

Identification and localization of morphological feature-specific metabolites in Reynoutria multiflora roots

MT Cai, Y Zhou, WL Ding, YH Huang, YS Ren… - Phytochemistry, 2023 - Elsevier
Reynoutria multiflora roots are a classical herbal medicine with unique nourishing
therapeutic effects. Anomalous vascular bundle (AVB) forming “cloudy brocade patterns” is a …

Dammarane-type triterpenoids from Gynostemma longipes and their protective activities on hypoxia-induced injury in PC12 cells

H Liang, C Xiaojuan, LI Qi, M Zhang… - Chinese Journal of …, 2024 - Elsevier
Sixteen new dammarane-type triterpenoid saponins (1–16) featuring diverse structural
variations in the side chain at C-17, along with twenty-one known analogues (17–37), have …

Insulin-mimetic activity of 23-glycosyl oleanane triterpenoids isolated from Gymnema latifolium

EJ Park, B Ryu, HJ Lee, TP Doan, HM Cho, WK Oh - Phytochemistry, 2023 - Elsevier
Chemical investigation of the plant Gymnema latifolium led to the isolation of seven
undescribed 23-glycosyl oleanane triterpenoids, gymlatinosides GLF1-GLF7, and two …

The aging of skeletal muscle and potential therapeutic effects of extracts from edible and inedible plants

NM Alfarafisa, K Kitaguchi, T Yabe - Reviews in Agricultural Science, 2020 - jstage.jst.go.jp
Sarcopenia is a degenerative phenomenon, common in elderly populations. As humans
age, they are likely to experience skeletal muscle weakness and atrophy; however …