Low diversity gut microbiota dysbiosis: drivers, functional implications and recovery

M Kriss, KZ Hazleton, NM Nusbacher, CG Martin… - Current opinion in …, 2018 - Elsevier
Highlights•Drivers of low-diversity dysbiosis include antibiotics, host genetics,
physiology.•Dysbiosis results in shifts in microbial composition and function.•Dysbiosis …

The gut-kidney axis: putative interconnections between gastrointestinal and renal disorders

M Lehto, PH Groop - Frontiers in endocrinology, 2018 - frontiersin.org
Diabetic kidney disease (DKD) is a devastating condition associated with increased
morbidity and premature mortality. The etiology of DKD is still largely unknown. However …

Clinical remission of ulcerative colitis after different modes of faecal microbiota transplantation: a meta-analysis

L Tang, W Feng, J Cheng, Y Gong - International Journal of Colorectal …, 2020 - Springer
Background Ulcerative colitis (UC) is a chronic, recurrent and destructive disease of the
gastrointestinal tract. Faecal microbiota transplantation (FMT) is a therapeutic measure in …

Inflammatory bowel disease and targeted oral anti-TNFα therapy

OR Griffiths, J Landon, RE Coxon, K Morris… - Advances in protein …, 2020 - Elsevier
Antibodies have provided invaluable treatment options for many diseases, with
immunotherapy revolutionising the treatment of several inflammatory disorders including …

Combined nutraceuticals: a novel approach to colitis-associated colorectal cancer?

LC Chartier, GS Howarth, S Mashtoub - Nutrition and cancer, 2019 - Taylor & Francis
Ulcerative colitis is an unremitting and lifelong inflammatory bowel disease that is increasing
in prevalence worldwide. Patients display various clinical symptoms such as abdominal …

Fecal microbiota transplantation donation: the gift that keeps on giving

EP Turse, FE Dailey, YA Ghouri, V Tahan - Current opinion in …, 2019 - Elsevier
Fecal microbiota transplantation (FMT) is being studied and utilized for various medical
conditions including Clostridium difficile colitis, inflammatory bowel diseases (IBD), obesity …

Active bacterial communities of pig fecal microbiota transplantation suspension prepared and preserved under different conditions

C Lin, J Wan, Y Lu, H Zhang, X Chen, Y Su, W Zhu - AMB Express, 2019 - Springer
Although fecal microbiota transplantation (FMT) has become a research hotspot, studies on
comparison of the active fecal bacteria suspension under different preparation conditions …

The development and preclinical assessment of ovine anti-TNF-α polyclonal antibodies for the oral treatment of inflammatory bowel disease

OR Griffiths - 2022 - figshare.cardiffmet.ac.uk
Tumour Necrosis Factor-alpha (TNF-α) is one of the main drivers of inflammatory bowel
disease (IBD). Regulating the actions of this pro-inflammatory cytokine through selective …

Causality between Gut Microbiota and Inflammatory Bowel Disease: A Bidirectional Mendelian Randomization Study

Q Zheng, Y Li, J Ni, Y Huang, J Wu, X Xu… - Infectious Microbes & …, 2023 - journals.lww.com
The exact relationship between inflammatory bowel disease (IBD) and gut microbiota (GM)
is still unclear. This study aimed to explore the cause-and-effect relationship between IBD …

Developing nanoparticulate oligonucleotides as a target-specific antimicrobial for modulation of complex gut microbiota

N Wong - 2018 - ueaeprints.uea.ac.uk
Developing nanoparticulate oligonucleotides as a target-specific antimicrobial for
modulation of complex gut microbiota The complex human gut microbiota harbours trillions …