Background Inflammation in the lung is the body's natural response to injury. It acts to
remove harmful stimuli such as pathogens, irritants, and damaged cells and initiate the …

The benefits of drug therapy for asthma have been well established, but adherence to
treatment is poor, and this might be associated with an increased risk of asthma …

Summary Background Fixed-dose combinations (FDCs) of inhaled corticosteroids (ICS) and
long-acting β 2-adrenoceptor agonists (LABA) are considered safe and efficacious in …

Airway remodeling is characterized by airway wall thickening, subepithelial fibrosis,
increased smooth muscle mass, angiogenesis and an increase in mucous glands, which …

Background Adherence to evidence-based controller treatments for asthma is
disappointingly low in many jurisdictions. Quantifying the burden associated with suboptimal …

Background In patients with asthma, particularly severe asthma, poor adherence to inhaled
drugs negatively affects the achievement of disease control. A better adherence rate is …

Modeled or simulated claims for costs and outcomes are a key element in formulary
submissions and comparative assessments of drug products and devices; however, all too …

Corticosteroids are the most effective treatment for asthma, but the therapeutic response
varies markedly between individuals, with up to one third of patients showing evidence of …

Health care cost of asthma treatment is enormous and medication adherence is the
cornerstone to improving the patient's quality of life, reducing overall health care cost, and …

Background A once-daily (od) fixed-dose combination of indacaterol acetate (IND),
glycopyrronium bromide (GLY), and mometasone furoate (MF) delivered via the …