The potential mechanism of Liu–Wei–Di–Huang Pills in treatment of type 2 diabetic mellitus: From gut microbiota to short-chain fatty acids metabolism
Z Yi, L Chen, Y Wang, D He, D Zhao, S Zhang, R Yu… - Acta Diabetologica, 2022 - Springer
Background Type 2 diabetes mellitus (T2DM) has already become a global pandemic.
Recently, reports showed its pathogenesis was closely related to a disorder of gut …
Recently, reports showed its pathogenesis was closely related to a disorder of gut …
Neurovascular glial unit: A target of phytotherapy for cognitive impairments
L Chen, Y Zhen, X Wang, J Wang, G Zhu - Phytomedicine, 2023 - Elsevier
Background Neurovascular glial unit (NVGU) dysfunction has been reported to be an early
and critical event in the pathophysiology of Alzheimer's disease (AD) and vascular dementia …
and critical event in the pathophysiology of Alzheimer's disease (AD) and vascular dementia …
Chronic corticosterone exposure impairs emotional regulation and cognitive function through disturbing neural oscillations in mice
S Zhao, X Xu, G Xie, T Zhang - Behavioural Brain Research, 2022 - Elsevier
Corticosterone is a stress hormone, which is often associated with a variety of the central
nervous system diseases. The study was to investigate the effects of Chronic corticosterone …
nervous system diseases. The study was to investigate the effects of Chronic corticosterone …
Application and advantages of zebrafish model in the study of neurovascular unit
D Lu, R Ma, Q Xie, Z Xu, J Yuan, M Ren, J Li… - European Journal of …, 2021 - Elsevier
Abstract The concept of “Neurovascular Unit”(NVU) was put forward, so that the research
goal of Central Nervous System (CNS) diseases gradually transitioned from a single neuron …
goal of Central Nervous System (CNS) diseases gradually transitioned from a single neuron …
Stachyose Alleviates Corticosterone-Induced Long-Term Potentiation Impairment via the Gut–Brain Axis
Y Huang, D Li, C Wang, N Sun, WX Zhou - Frontiers in Pharmacology, 2022 - frontiersin.org
Stress can induce learning and memory impairment; corticosterone is often used to study the
effects and mechanisms of stress in animal models. Long-term potentiation (LTP) has been …
effects and mechanisms of stress in animal models. Long-term potentiation (LTP) has been …
Active fraction combination from Liuwei Dihuang decoction improves adult hippocampal neurogenesis and neurogenic microenvironment in cranially irradiated mice
M Wei, S Feng, L Zhang, C Wang, S Chu… - Frontiers in …, 2021 - frontiersin.org
Background: Cranial radiotherapy is clinically used in the treatment of brain tumours;
however, the consequent cognitive and emotional dysfunctions seriously impair the life …
however, the consequent cognitive and emotional dysfunctions seriously impair the life …
LiuweiDihuang improved cognitive functions in SAMP8 mice by inhibiting COX-2 expression and subsequent neuroinflammation
J Song, Y Jia, J Li, R Ding, Y Yuan, J Cai, Y Su… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance LiuweiDihuang (LW) pills was mainly used to treatment of
children's fontanelle incomplete closure, enuresis and nervous system development delays …
children's fontanelle incomplete closure, enuresis and nervous system development delays …
Liuwei Dihuang formula ameliorates chronic stress-induced emotional and cognitive impairments in mice by elevating hippocampal O-GlcNAc modification
Y Huang, J Wang, F Liu, C Wang, Z Xiao… - Frontiers in …, 2023 - frontiersin.org
A substantial body of evidence has indicated that intracerebral O-linked N-acetyl-β-D-
glucosamine (O-GlcNAc), a generalized post-translational modification, was emerging as an …
glucosamine (O-GlcNAc), a generalized post-translational modification, was emerging as an …
Exploring the protective effect of morroniside on neuroinflammation based on combined GEO analysis and molecular docking experiments
J Lu, M Zhou, C Cai, R Zheng, W Guo… - … on Biomedical and …, 2024 - spiedigitallibrary.org
This study aims to explore the molecular mechanisms and protective effects of
Monoisobutyrate on lipopolysaccharide (LPS)-induced inflammatory damage in microglial …
Monoisobutyrate on lipopolysaccharide (LPS)-induced inflammatory damage in microglial …