Spike timing-dependent plasticity (STDP) is a Hebbian learning rule important for synaptic
refinement during development and for learning and memory in the adult. Given the …

The transmembrane protein deleted in colorectal cancer (DCC) and its ligand, netrin-1,
regulate synaptogenesis during development, but their function in the mature central …

Major depressive disorder (MDD) is considered a 'circuitopathy', and brain stimulation
therapies hold promise for ameliorating MDD symptoms, including hippocampal dysfunction …

Repetitive transcranial magnetic stimulation (rTMS) is a widely-used method for modulating
cortical excitability in humans, by mechanisms thought to involve use-dependent synaptic …

Perfluorooctane sulfonate (PFOS), a persistent and bioaccumulative compound, is widely
distributed in the environment. To explore the molecular mechanism of neonatal neurotoxic …

Evidence shows that the serine/threonine protein phosphatase 1 (PP1) plays a critical role in
synaptic plasticity and memory. Little is known about the contribution of the serine/threonine …

Clinical studies have shown that cathodal transcranial direct-current stimulation (tDCS)
application can produce long-term suppressive effects on drug-resistant seizures. Whether …

The modulatory neurotransmitter dopamine induces concentration-dependent changes in
synaptic transmission in the entorhinal cortex, in which high concentrations of dopamine …

Despite the advent of transgenic gene manipulation in vivo and in vitro and the rapid rise of
RNA interference, in order to target protein function by ablation or suppression of specific …

The superficial layers of the entorhinal cortex receive sensory and associational cortical
inputs and provide the hippocampus with the majority of its cortical sensory input. The …