Biodegradable poly (lactic acid)(PLA) presents suitable physicochemical properties and
biocompatibility for biomedical engineering. However, PLA has some drawbacks, such as …

Over millions of years of evolution, nature has created organisms with overwhelming
performances due to their unique materials and structures, providing us with valuable …

Patient-derived organoids (PDOs) can model personalized therapy responses; however,
current screening technologies cannot reveal drug response mechanisms or how tumor …

Over the recent decades gelatin has proven to be very suitable as an extracellular matrix
mimic for biofabrication and tissue engineering applications. However, gelatin is prone to …

Immune escape is central to the persistence of most, if not all, solid tumors and poses a
critical obstacle to successful cancer (immuno) therapy. Cancer-associated fibroblasts …

Designer self‐assembling peptides form the entangled nanofiber networks in hydrogels by
ionic‐complementary self‐assembly. This type of hydrogel has realistic biological and …

Scaffolds are important physical substrates for cell attachment, proliferation and
differentiation. Multiple factors could influence the optimal design of scaffolds for a specific …

Rationale: The tumor microenvironment (TME) determines tumor progression and affects
clinical therapy. Its basic components include cancer-associated fibroblasts (CAFs) and …

Peritoneal metastasis (PM) occurs in approximately one in four colorectal cancer (CRC)
patients. The pathophysiology of colorectal PM remains poorly characterized. Also, the …

Polyester-based scaffolds have been employed in tissue engineering due to their
biocompatibility, biodegradability, microstructure, and affordability. However, the acidic …