Turquoise killifish (Nothobranchius furzeri) are naturally short-lived vertebrates that display a
wide range of spontaneous age-related changes, including onset of cancer, reduced …

Thanks to medical and technological improvements, our world population has become ever-
greying. In consequence, the incidence and prevalence of age-related central nervous …

The African turquoise killifish is a powerful vertebrate system to study complex phenotypes
at scale, including aging and age-related disease. Here, we develop a rapid and precise …

Age‐related vision loss caused by retinal neurodegenerative pathologies is becoming more
prevalent in our ageing society. To understand the physiological and molecular impact of …

Aging and neurodegeneration entail diverse cellular and molecular hallmarks. Here, we
studied the effects of aging on the transcriptome, translatome, and multiple layers of the …

The African turquoise killifish is a powerful vertebrate system to study complex phenotypes
at scale, including aging and age-related disease. Here we develop a rapid and precise …

Post-translational modifications (PTMs) regulate protein homeostasis and function. How
aging affects the landscape of PTMs remains largely elusive. Here, we reveal changes in …

Amyloid beta (Aβ) accumulation is associated with inflammation, neurodegeneration, and
cognitive decline in the context of neurodegenerative diseases. However, the effect of Aβ …

The short-lived annual fish Nothobranchius furzeri (Nfu) has an extremely short life span and
accelerated expression of age markers. This animal model recapitulates the major features …