Sustainable drug discovery of multi-target-directed ligands for Alzheimer's disease

M Rossi, M Freschi… - Journal of medicinal …, 2021 - ACS Publications
The multifactorial nature of Alzheimer's disease (AD) is a reason for the lack of effective
drugs as well as a basis for the development of “multi-target-directed ligands”(MTDLs). As …

[HTML][HTML] Exploring the potential of cashew waste for food and health applications-A review

N Aslam, SA Hassan, F Mehak, S Zia, ZF Bhat… - Future Foods, 2024 - Elsevier
Nowadays, the effective utilization of food waste presents a significant challenge for the food
industry. The transformation of food waste materials into useful products, and the production …

Cashew nut shell liquid (CNSL) as a source of drugs for Alzheimer's disease

E Uliassi, AS de Oliveira, L de Camargo Nascente… - Molecules, 2021 - mdpi.com
Alzheimer's disease (AD) is a complex neurodegenerative disorder with a multifaceted
pathogenesis. This fact has long halted the development of effective anti-AD drugs …

Influence of techniques on synthesizing cashew nut shell oil as a prospective biolubricant on its physicochemical, tribological, and thermal behaviors

P Prasannakumar, S Sankarannair, C Bose… - Journal of Cleaner …, 2023 - Elsevier
Rising demand for lubricants and temperamental government policies hastened the need for
a renewable base stock for petroleum-based lubricants. The environment-friendly alternative …

Anti-inflammatory, antinociceptive, and antioxidant properties of anacardic acid in experimental models

AL Gomes Junior, MT Islam, LAD Nicolau… - ACS …, 2020 - ACS Publications
Anacardic acid (AA), a compound extracted from cashew nut liquid, exhibits numerous
pharmacological activities. The aim of the current investigation was to assess the anti …

Identification and Quantification of Bioactive Compounds in Diaphragma juglandis Fructus by UHPLC-Q-Orbitrap HRMS and UHPLC-MS/MS

R Liu, Z Zhao, S Dai, X Che, W Liu - Journal of agricultural and …, 2019 - ACS Publications
Diaphragma juglandis fructus is the dry wooden diaphragm inside walnuts and a byproduct
in food processing of walnut kernels. The purpose of our research is to enrich the …

Antimicrobial effect of anacardic acid–loaded zein nanoparticles loaded on Streptococcus mutans biofilms

RA Lima, SLX de Souza, LA Lima, ALX Batista… - Brazilian journal of …, 2020 - Springer
Bacterial biofilms play a key role in the pathogenesis of major oral diseases. Nanoparticles
open new paths for drug delivery in complex structures such as biofilms. This study …

[HTML][HTML] Cashew nut shell liquids: Antimicrobial compounds in prevention and control of the oral biofilms

N de Oliveira Souza, DA Cunha… - Archives of oral …, 2022 - Elsevier
Objective The aim was to evaluate the antibacterial and antibiofilm activity of natural (n-
CNSL) and technical (t-CNSL) cashew nut shell liquid against streptococci and enterococci …

Phenolic lipids derived from cashew nut shell liquid to treat metabolic diseases

C Sahin, L Magomedova, TAM Ferreira… - Journal of Medicinal …, 2022 - ACS Publications
Metabolic diseases are increasing at staggering rates globally. The peroxisome proliferator-
activated receptors (PPARα/γ/δ) are fatty acid sensors that help mitigate imbalances …

Nuts and nut-based products: A meta-analysis from intake health benefits and functional characteristics from recovered constituents

G Polmann, V Badia, R Danielski… - Food Reviews …, 2023 - Taylor & Francis
This review provides information on nutritional characteristics, extraction techniques,
bioactive compounds, bioavailability and bioaccessibility through in vitro and in vivo assays …