Warburg effect, lactate dehydrogenase, and radio/chemo-therapy efficacy

MI Koukourakis, A Giatromanolaki - International Journal of …, 2019 - Taylor & Francis
The anaerobic metabolism of glucose by cancer cells, even under well-oxygenated
conditions, has been documented by Otto Warburg as early as 1927. Micro-environmental …

The prognostic value of hematological and systemic inflammatory disorders in invasive bladder cancer

G Gakis, T Todenhöfer, A Stenzl - Current opinion in urology, 2011 - journals.lww.com
The degree of systemic inflammation and hematological disorders in invasive bladder
cancer is often associated with more aggressive disease. The incorporation of hemoglobin …

Preoperative neutrophil/lymphocyte ratio predicts overall survival and extravesical disease in patients undergoing radical cystectomy

LS Krane, KA Richards, AK Kader, R Davis… - Journal of …, 2013 - liebertpub.com
Purpose: To evaluate if hematologic parameters and inflammatory markers could predict
extravesical tumor and overall survival after radical cystectomy for patients with recurrent …

Preoperative anemia and low hemoglobin level are associated with worse clinical outcomes in patients with bladder cancer undergoing radical cystectomy: a meta …

L Xia, TJ Guzzo - Clinical genitourinary cancer, 2017 - Elsevier
Purpose The aim of this study was to determine the effect of preoperative anemia status and
hemoglobin level on clinical outcomes in patients with bladder cancer undergoing radical …

Association between pretreatment haemoglobin levels and morphometric characteristics of the tumour, response to neoadjuvant treatment and long‐term outcomes in …

AA Khan, M Klonizakis, A Shabaan… - Colorectal …, 2013 - Wiley Online Library
Aim The study was carried out to investigate whether pretreatment haemoglobin (Hb) levels
act as a biomarker in the management of patients with locally advanced rectal cancer …

Prognostic impact of preoperative hematological disorders and a risk stratification model in bladder cancer patients treated with radical cystectomy

T Sejima, S Morizane, A Yao, T Isoyama… - … Journal of Urology, 2014 - Wiley Online Library
Objectives The present study investigated prognostic indicators, including
clinicopathological and preoperative hematological factors, and developed a prognostic …

Preoperative prognostic factors after radical nephroureterectomy in patients with upper urinary tract urothelial carcinoma

S Morizane, H Iwamoto, T Masago, A Yao… - … urology and nephrology, 2013 - Springer
Purpose To evaluate the clinical significance of preoperative biomarkers such as laboratory
data, Eastern Cooperative Oncology Group Performance Status (ECOG PS) and …

The prognostic role of pre-cystectomy hemoglobin levels in patients with invasive bladder cancer

T Schubert, T Todenhöfer, J Mischinger… - World journal of …, 2016 - Springer
Purpose To determine whether pre-treatment hemoglobin (Hb) levels in patients with
bladder cancer impact on oncological outcomes after radical cystectomy (RC). Methods A …

[HTML][HTML] Significant prognostic impact of chemoradiotherapy-induced hemoglobin decrease on treatment outcomes of nasopharyngeal carcinoma

XX Liang, Q Li, Z Su, XW Lan, PY Ouyang… - Journal of …, 2015 - ncbi.nlm.nih.gov
Purpose: To investigate prognostic impact of chemoradiotherapy-induced hemoglobin (Hb)
decrease on treatment outcomes of endemic nasopharyngeal carcinoma (NPC). Materials …

Prognostic implications of preoperative anemia in urothelial carcinoma: A meta-analysis

F Luo, YS Wang, YH Su, ZH Zhang, HH Sun, J Li - PLoS One, 2017 - journals.plos.org
The prognostic significance of preoperative anemia (PA) has been identified in various
malignancies. However, its predictive role in urothelial carcinoma (UC) remains …