Evidence, challenges, and knowledge gaps regarding latent tuberculosis in animals

P Ncube, B Bagheri, WJ Goosen, MA Miller… - Microorganisms, 2022 - mdpi.com
Mycobacterium bovis and other Mycobacterium tuberculosis complex (MTBC) pathogens
that cause domestic animal and wildlife tuberculosis have received considerably less …

Advancing animal tuberculosis surveillance using culture-independent long-read whole-genome sequencing

G Ghielmetti, J Loubser, TJ Kerr, T Stuber… - Frontiers in …, 2023 - frontiersin.org
Animal tuberculosis is a significant infectious disease affecting both livestock and wildlife
populations worldwide. Effective disease surveillance and characterization of …

Antemortem detection of Mycobacterium bovis in nasal swabs from African rhinoceros

R Dwyer, C Witte, P Buss, R Warren, M Miller… - Scientific Reports, 2024 - nature.com
Mycobacterium bovis (M. bovis) infection has been identified in black (Diceros bicornis) and
white (Ceratotherium simum) rhinoceros populations in Kruger National Park, South Africa …

[HTML][HTML] Identification and molecular characterization of Mycobacterium bovis DNA in GeneXpert® MTB/RIF ultra-positive, culture-negative sputum from a rural …

WJ Goosen, S Moodley, G Ghielmetti, Y Moosa, T Zulu… - One Health, 2024 - Elsevier
This study investigated the presence of Mycobacterium bovis (M. bovis) DNA in archived
human sputum samples previously collected from residents who reside adjacent to the M …

Epidemiology of Mycobacterium bovis infection in free-ranging rhinoceros in Kruger National Park, South Africa

R Dwyer, W Goosen, P Buss… - Proceedings of the …, 2022 - National Acad Sciences
Mycobacterium bovis infection, which is a prominent cause of bovine tuberculosis, has been
confirmed by mycobacterial culture in African rhinoceros species in Kruger National Park …

Assessment of the frequency of Mycobacterium bovis shedding in the faeces of naturally and experimentally TB infected cattle

S Palmer, GA Williams, C Brady, E Ryan… - Journal of applied …, 2022 - Wiley Online Library
Aims To assess the prevalence of Mycobacterium bovis bacilli in faecal samples of
tuberculous cattle, and to better understand the risk of environmental dissemination of …

Insights into mycobacteriome composition in Mycobacterium bovis-infected African buffalo (Syncerus caffer) tissue samples

G Ghielmetti, TJ Kerr, N Bernitz, SK Mhlophe… - Scientific Reports, 2024 - nature.com
Animal tuberculosis significantly challenges global health, agriculture, and wildlife
conservation efforts. Mycobacterial cultures are resource-intensive, time-consuming, and …

Culture-independent PCR detection and differentiation of mycobacteria spp. in antemortem respiratory samples from African elephants (Loxodonta africana) and …

WJ Goosen, C Clarke, L Kleynhans, TJ Kerr, P Buss… - Pathogens, 2022 - mdpi.com
Since certain Mycobacterium tuberculosis complex (MTBC) members, such as M. bovis, are
endemic in specific South African wildlife reserves and zoos, cases of clinically important …

Detection of Mycobacterium bovis in nasal swabs from communal goats (Capra hircus) in rural KwaZulu-Natal, South Africa

DM Cooke, C Clarke, TJ Kerr, RM Warren… - Frontiers in …, 2024 - frontiersin.org
Animal tuberculosis, caused by Mycobacterium bovis, presents a significant threat to both
livestock industries and public health. Mycobacterium bovis tests rely on detecting antigen …

Bayesian accuracy estimates for diagnostic tests to detect tuberculosis in captive sun bears (Helarctos malayanus) and Asiatic black bears (Ursus thibetanus) in …

K Officer, JC Arango-Sabogal, S Dufour… - PloS one, 2024 - journals.plos.org
Effective control of tuberculosis (TB) depends on early diagnosis of disease, yet available
tests are unable to perfectly detect infected individuals. In novel hosts diagnostic testing …